1887

Abstract

SUMMARY: Aggregations involving mixtures of wild-type and ‘aggregateless’ mutant organisms of were examined. The proportions of wild-type individuals which could initiate the formation of aggregative centres by their neighbours was found to depend markedly upon the particular mutant in the mixture. The mutants appear to have supplied some of the cells responding to the initiative stimulus where these were needed and also to have produced diffusible material enabling many more wild-type organisms to act as initiators than would ordinarily do so. The results also indicate the existence of a variety of cellular interactions which may underlie the normal morphogenetic sequence.

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/content/journal/micro/10.1099/00221287-18-2-433
1958-04-01
2021-07-28
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References

  1. Bonner J.T. 1947; Evidence for the formation of cell aggregation by ehemotaxis in the development of the slime mold,Dictyosteliumdiscoideum. . J. exp. Zool 106:1
    [Google Scholar]
  2. Bonner J.T., Frascella E.B. 1953; Variation in cell size during the development of the slime mold,Dictyosteliumdiscoideum. . Biol. Bull.,Wood’sHole 104:297
    [Google Scholar]
  3. Bonner J.T., Slifkin M. 1949; Study of the control of differentiation: proportions of spore and stalk cells in the slime mold,Dictyosteliumdiscoideum. . Amer. J. Bot 36:727
    [Google Scholar]
  4. Bradley S.G., Sussman M., Ennis H.L. 1956; Environmental factors affecting the aggregation of the cellular slime mold,Dictyosteliumdiscoideum. . J. Protozool 3:33
    [Google Scholar]
  5. Davis B.D. 1950; Studies on nutritionally deficient bacterial mutants isolated with penicillin. Experimentia 6:41
    [Google Scholar]
  6. Gregg J.H. 1957; Serological investigations of aggregateless variants of the slime mold,Dictyosteliumdiscoideum. . Anat. Rec 128:558
    [Google Scholar]
  7. Grobstein C. 1956; Inductive tissue interaction in development. Advanc.Cancer Res 4:221
    [Google Scholar]
  8. Sussman M. 1951; Origin of cellular heterogeneity in the development of the slime molds, Dictyosteliaceae. J. exp. Zool 118:407
    [Google Scholar]
  9. Sussman M. 1952; An analysis of the aggregation stage in the development of the slime molds, Dictyostelliaceae. II. Aggregative center formation by mixtures ofDictyosteliumdiscoideumwild type and aggregateless variants. Biol. Bull.Woods Hole 103:446
    [Google Scholar]
  10. Sussman M. 1954; Synergistic and antagonistic interactions between morpho- genetically deficient variants of the slime mould,Dictyosteliumdiscoideum. . J. gen. Microbiol 10:11
    [Google Scholar]
  11. Sussman M. 1955; ’Fruity’ and other mutants of the cellular slime mould.Dictyosteliumdiscoideum:a study of developmental aberrations. J. gen. Microbiol 13:295
    [Google Scholar]
  12. Sussman M. 1956; On the relation between growth and morphogenesis in the slime mold,Dictyosteliumdiscoideum. . Biol. Bull. Woods Hole 110:91
    [Google Scholar]
  13. Sussman M., Lee F. 1955; Interactions among variant and wild type strains of cellular slime molds across thin agar membranes. Proc. nat. Acad. Sci., Wash 41:70
    [Google Scholar]
  14. Sussman M., Noel E. 1952; An analysis of the aggregation stage in the development of the slime molds, Dictyosteliaceae. I. The populational distribution of the capacity to initiate aggregation. Biol. Bull. Woods Hole 103:259
    [Google Scholar]
  15. Sussman R.R., Sussman M. 1953; Cellular differentiation in Dictyosteliaceae: heritable modifications of the developmental pattern. Ann. N.Y. Acad. Sci 56:949 Art. 5
    [Google Scholar]
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