1887
Preview this article:
Zoom in
Zoomout

Replicative ageing and senescence in and the impact on brewing fermentations, Page 1 of 1

| /docserver/preview/fulltext/micro/146/5/1461023a-1.gif

There is no abstract available for this article.
Use the preview function to the left.

Keyword(s): ageing , brewing , lifespan , senescence and yeast
Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-146-5-1023
2000-05-01
2019-10-17
Loading full text...

Full text loading...

/deliver/fulltext/micro/146/5/1461023a.html?itemId=/content/journal/micro/10.1099/00221287-146-5-1023&mimeType=html&fmt=ahah

References

  1. Aparicio, O. M., Billington, B. L. & Gottschling, D. E. ( 1991; ). Modifiers of position effect are shared between telomeric and silent mating-type loci in Saccharomyces cerevisiae. Cell 66, 1279-1287.[CrossRef]
    [Google Scholar]
  2. Austriaco, N. R. ( 1996; ). To bud until death: the genetics of ageing in the yeast, Saccharomyces. Yeast 12, 623-630.[CrossRef]
    [Google Scholar]
  3. Austriaco, N. & Guarente, L. ( 1997; ). Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 94, 9768-9772.[CrossRef]
    [Google Scholar]
  4. Barker, M. G. & Smart, K. A. ( 1996; ). Morphological changes associated with the cellular ageing of a brewing yeast strain. J Am Soc Brew Chem 54, 121-126.
    [Google Scholar]
  5. Barker, M. G., Brimage, L. J. E. & Smart, K. A. ( 1999; ). Effect of Cu,Zn superoxide dismutase disruption mutation on replicative senescence in Saccharomyces cerevisiae. FEMS Microbiol Lett 177, 199-204.[CrossRef]
    [Google Scholar]
  6. Bartholomew, J. W. & Mittwer, T. ( 1953; ). Demonstration of yeast bud scars with the electron microscope. J Bacteriol 65, 272-275.
    [Google Scholar]
  7. Barton, A. A. ( 1950; ). Some aspects of cell division in Saccharomyces cerevisiae. J Gen Microbiol 4, 84-86.[CrossRef]
    [Google Scholar]
  8. Bell, S. P. & Stillman, B. ( 1992; ). ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature 357, 128-134.[CrossRef]
    [Google Scholar]
  9. Berger, K. B. & Yaffe, M. P. ( 1998; ). Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae. Mol Cell Biol 18, 4043-4052.
    [Google Scholar]
  10. Breeden, L. ( 1996; ). Start-specific transcription in yeast. Curr Top Microbiol Immunol 208, 95-127.
    [Google Scholar]
  11. Campisi, J. ( 1996; ). Replicative senescence: an old lives’ tale? Cell 84, 497-500.[CrossRef]
    [Google Scholar]
  12. Campisi, J., Dimri, G. & Hara, E. ( 1996; ). Control of replicative senescence. In Handbook of the Biology of Ageing, pp. 121-149. Edited by E. Schneider & J. Rowe. New York: Academic Press.
  13. Childress, A. M., Franklin, D. S., Pinswasdi, C., Kale, S. & Jazwinski, S. M. ( 1996; ). LAG2, a gene that determines yeast longevity. Microbiology 142, 2289-2297.[CrossRef]
    [Google Scholar]
  14. Chiu, C. P. & Harley, C. B. ( 1997; ). Replicative senescence and cell immortality: the role of telomeres and telomerase. Proc Soc Exp Biol Med 214, 99-106.[CrossRef]
    [Google Scholar]
  15. Coates, P. J., Jamieson, D. J., Smart, K. A. & Hall, P. A. ( 1997; ). The prohibitin family of mitochondrial proteins regulate replicative lifespan. Curr Biol 7, R607-R610.[CrossRef]
    [Google Scholar]
  16. Commenor, B., Townsend, J. & Pake, G. E. ( 1954; ). Free radicals in biological materials. Nature 174, 689-691.[CrossRef]
    [Google Scholar]
  17. D’Amore, T. ( 1992; ). Improving yeast fermentation performance. J Inst Brew 98, 375-382.[CrossRef]
    [Google Scholar]
  18. Day, A. W., Poon, N. H. & Stewart, G. G. ( 1975; ). Fungal fimbriae. III. The effect on flocculation in Saccharomyces cerevisiae. Can J Microbiol 12, 558-564.
    [Google Scholar]
  19. Deans, K., Pinder, A., Catley, B. J. & Hodgson, J. A. ( 1997; ). Effects of cone cropping and serial repitch on the distribution of cell ages in brewery yeast. Proc Eur Brew Con 26, 469-476.
    [Google Scholar]
  20. Diffley, J. F. ( 1995; ). The initiation of DNA replication in the budding yeast cell division cycle. Yeast 11, 1651-1670.[CrossRef]
    [Google Scholar]
  21. Diffley, J. F. & Cocker, J. H. ( 1992; ). Protein–DNA interactions at a yeast replication origin. Nature 357, 169-172.[CrossRef]
    [Google Scholar]
  22. D’mello, N. P. & Jazwinski, S. M. ( 1991; ). Telomere length constancy during aging of Saccharomyces cerevisiae. J Bacteriol 173, 6709-6713.
    [Google Scholar]
  23. D’mello, N. P., Childress, A. M., Kale, S. P., Pinswadi, C. & Jazwinski, S. M. ( 1994; ). Cloning and characterisation of LAG1, a longevity assurance gene in yeast. J Biol Chem 269, 15451-15459.
    [Google Scholar]
  24. Egilmez, N. K. & Jazwinski, S. M. ( 1989; ). Evidence for the involvement of a cytoplasmic factor in the aging of the yeast Saccharomyces cerevisiae. J Bacteriol 171, 37-42.
    [Google Scholar]
  25. Egilmez, N. K., Chen, J. B. & Jazwinski, S. M. ( 1989; ). Specific alterations in transcript prevalence during the yeast life-span. J Biol Chem 264, 14312-14317.
    [Google Scholar]
  26. Egilmez, N. K., Chen, J. B. & Jazwinski, S. M. ( 1990; ). Preparation and partial characterisation of old yeast cells. J Gerontol 45, B9-B17.[CrossRef]
    [Google Scholar]
  27. Fleming, J. E., Walton, J. K., Dubitsky, R. & Bensch, J. G. ( 1988; ). Aging results in an unusual expression of Drosophila heat-shock proteins. Proc Natl Acad Sci USA 85, 4099-4103.[CrossRef]
    [Google Scholar]
  28. Forsburg, S. L. ( 1994; ). Cell cycle – in and out of the cell cycle. Curr Biol 4, 828-830.[CrossRef]
    [Google Scholar]
  29. Forsburg, S. L. & Nurse, P. ( 1991; ). Cell-cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Annu Rev Cell Biol 7, 227-256.[CrossRef]
    [Google Scholar]
  30. Futcher, B. ( 1993; ). Analysis of the cell cycle in Saccharomyces cerevisiae. In The Cell Cycle: a Practical Approach, pp. 69-92. Edited by P. Fantes & R. Brooks. Oxford: IRL Press.
  31. Futcher, B. ( 1996; ). Cyclins and the wiring of the yeast cell cycle. Yeast 12, 1635-1646.[CrossRef]
    [Google Scholar]
  32. George, E. (1996). The influence of brewing yeast physiology on cell surface physical properties. PhD thesis, Oxford Brookes University.
  33. Goletz, T. J., Smith, J. R. & Pereira-Smith, O. M. ( 1994; ). Molecular genetic approaches to the study of cellular senescence. Cold Spring Harbor Symp Quant Biol 59, 59-66.[CrossRef]
    [Google Scholar]
  34. Grant, C. M., MacIver, F. H. & Dawes, I. W. ( 1997; ). Mitochondrial function is required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae. FEBS Lett 410, 219-222.[CrossRef]
    [Google Scholar]
  35. Guidot, D. M., McCord, J. M., Wright, R. M. & Repine, J. E. ( 1993; ). Absence of electron transport (Rho0 state) restores growth of a manganese-superoxide dismutase-deficient Saccharomyces cerevisiae in hyperoxia. J Biol Chem 268, 26699-26703.
    [Google Scholar]
  36. Haber, J. E. & Thornburn, P. C. ( 1984; ). Healing of broken linear dicentric chromosomes in yeast. Genetics 106, 207-226.
    [Google Scholar]
  37. Hammond, J. R. M. ( 1993; ). Brewers yeast. In The Yeasts, pp. 7-67. Edited by A. H. Rose & J. S. Harrison. London: Academic Press.
  38. Harley, C. B., Futcher, A. B. & Greider, C. W. ( 1990; ). Telomeres shorten during aging of human fibroblasts. Nature 345, 458-460.[CrossRef]
    [Google Scholar]
  39. Harman, D. ( 1956; ). Ageing: a theory based on free radical and radiation chemistry. J Gerontol 114, 298-300.
    [Google Scholar]
  40. Harman, D. ( 1981; ). The aging process. Proc Natl Acad Sci USA 78, 7124-7128.[CrossRef]
    [Google Scholar]
  41. Harman, D. ( 1992; ). Free radical theory of aging. Mutat Res 275, 257-266.[CrossRef]
    [Google Scholar]
  42. Hartwell, L. H. ( 1974; ). Saccharomyces cerevisiae cell cycle. Bacteriol Rev 38, 164-198.
    [Google Scholar]
  43. Hartwell, L. H. ( 1978; ). Cell division from a genetic perspective. J Cell Biol 77, 626-637.
    [Google Scholar]
  44. Hartwell, L. H. & Weinhart, T. A. ( 1989; ). Checkpoints – controls that ensure the order of cell-cycle events. Science 246, 629-634.[CrossRef]
    [Google Scholar]
  45. Hartwell, L. H., Culotti, J., Pringle, J. R. & Reid, B. ( 1974; ). Genetic control of the cell division cycle in yeast. Science 183, 46-51.[CrossRef]
    [Google Scholar]
  46. Hastie, N. D. & Allshire, R. C. ( 1989; ). Human telomeres: fusion and interstitial sites. Trends Genet 5, 326-331.[CrossRef]
    [Google Scholar]
  47. Hastie, N. D., Dempster, M., Dunlop, M. G., Thompson, A. M., Green, D. K. & Allshire, R. C. ( 1990; ). Telomere reduction in human colorectal carcinoma and with aging. Nature 346, 866-868.[CrossRef]
    [Google Scholar]
  48. Hayflick, L. ( 1965; ). The limited in vitro lifespan of human diploid cell strains. Exp Cell Res 37, 614-636.[CrossRef]
    [Google Scholar]
  49. Hayflick, L. & Moorhead, P. S. ( 1961; ). The serial cultivation of human diploid cell strains. Exp Cell Res 25, 585-621.[CrossRef]
    [Google Scholar]
  50. Holliday, R. ( 1996; ). Endless quest. Bioessays 18, 3-5.[CrossRef]
    [Google Scholar]
  51. Hough, J. S. ( 1961; ). Estimation of the age of cells in a population of yeast. J Inst Brew 67, 494-495.[CrossRef]
    [Google Scholar]
  52. James, A. P., Johnson, B. F., Inhaber, E. R. & Gridgeman, N. T. ( 1975; ). A kinetic analysis of spontaneous ψ mutations in yeast. Mutat Res 30, 199-208.[CrossRef]
    [Google Scholar]
  53. Jamieson, D. J. ( 1995; ). The effect of oxidative stress on Saccharomyces cerevisiae. Redox Rep 1, 89-95.
    [Google Scholar]
  54. Jamieson, D. J. ( 1998; ). Oxidative stress responses of the yeast Saccharomyces cerevisiae. Yeast 14, 1511-1527.[CrossRef]
    [Google Scholar]
  55. Jazwinski, S. M. ( 1990a; ). Aging and senescence of the budding yeast Saccharomyces cerevisiae. Mol Microbiol 4, 337-343.[CrossRef]
    [Google Scholar]
  56. Jazwinski, S. M. ( 1990b; ). An experimental system for the molecular analysis of the aging process: the budding yeast Saccharomyces cerevisiae. J Gerontol 45, B68-B74.[CrossRef]
    [Google Scholar]
  57. Jazwinski, S. M. ( 1993a; ). Genes of youth: genetics of aging in baker’s yeast. ASM News 59, 172-178.
    [Google Scholar]
  58. Jazwinski, S. M. ( 1993b; ). The genetics of aging in the yeast Saccharomyces cerevisiae. Genetica 91, 35-51.[CrossRef]
    [Google Scholar]
  59. Jazwinski, S. M. ( 1995; ). Nuclear genes in ageing. In Molecular Aspects of Aging, pp. 15-28. Edited by K. Esser & G. M. Martin. Chichester: Wiley.
  60. Jazwinski, S. M. ( 1996; ). Longevity, genes, and aging. Science 273, 54-58.[CrossRef]
    [Google Scholar]
  61. Johnson, T. E. ( 1997; ). Genetic influences on aging. Exp Gerontol 32, 11-22.[CrossRef]
    [Google Scholar]
  62. Johnson, B. F. & Lu, C. ( 1975; ). Morphometric analysis of yeast cells. IV. Increase of the cylindrical diameter of Schizosaccharomyces pombe during the cell cycle. Exp Cell Res 95, 154-158.[CrossRef]
    [Google Scholar]
  63. Kale, S. P. & Jazwinski, S. M. ( 1996; ). Differential response to UV stress and DNA damage during the yeast replicative life span. Dev Genet 18, 154-160.[CrossRef]
    [Google Scholar]
  64. Katz, M. L., Robison, W. G.Jr, Herrmann, R. K., Groome, A. B. & Bieri, J. G. ( 1984; ). Lipofuscin accumulation resulting from senescence and vitamin E deficiency: spectral properties and tissue distribution. Mech Ageing Dev 25, 149-159.[CrossRef]
    [Google Scholar]
  65. Kennedy, B. K. & Guarente, L. ( 1996; ). Genetic analysis of aging in Saccharomyces cerevisiae. Trends Genet 12, 355-358.[CrossRef]
    [Google Scholar]
  66. Kennedy, B. K., Austriaco, N. R. & Guarente, L. ( 1994; ). Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span. J Cell Biol 127, 1985-1993.[CrossRef]
    [Google Scholar]
  67. Kennedy, B. K., Austriaco, N. R., Zhang, J. & Guarente, L. ( 1995; ). Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell 80, 485-496.[CrossRef]
    [Google Scholar]
  68. Kenyon, C. ( 1996; ). Ponce d’elegans: genetic quest for the fountain of youth. Cell 84, 501-504.[CrossRef]
    [Google Scholar]
  69. Kirchman, P. A., Kim, S., Lai, C.-Y. & Jazwinski, S. M. ( 1999; ). Interorganelle signalling is a determinant of longevity in Saccharomyces cerevisiae. Genetics 152, 179-190.
    [Google Scholar]
  70. Kuntzel, H., Schultz, A. & Ehbrecht, I.-M. ( 1996; ). Cell cycle control and initiation of DNA replication in Saccharomyces cerevisiae. Biol Chem 377, 481-487.
    [Google Scholar]
  71. Lew, D. J. & Reed, S. I. ( 1995; ). A cell cycle checkpoint monitors cell morphogenesis in budding yeast. Curr Opin Genet Dev 129, 739-740.
    [Google Scholar]
  72. Lindsey, J., McGill, N. I., Lindsey, L. A., Green, D. K. & Cooke, H. J. ( 1991; ). In vivo loss of telomeric repeats with age in humans. Mutat Res 256, 45-48.[CrossRef]
    [Google Scholar]
  73. Longo, V. D., Gralla, E. B. & Valentine, J. S. ( 1996; ). Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. J Biol Chem 271, 12275-12280.[CrossRef]
    [Google Scholar]
  74. Loveridge, D., Ruddlesden, J. D., Noble, C. S. & Quain, D. E. (1999). Improvements in brewery fermentation performance by ‘early’ yeast cropping and reduced yeast storage time. In Proceedings of the 7th Scientific and Technical Convention, pp. 95–99. Nairobi: Institute of Brewing Africa Section.
  75. Lydall, D. & Weinert, T. ( 1996; ). From DNA damage to cell cycle arrest and suicide: a budding yeast perspective. Curr Opin Genet Dev 6, 4-11.[CrossRef]
    [Google Scholar]
  76. Lyons, T. P. & Hough, J. S. (1970). The role of yeast cell walls in brewing. Brew Dig Aug, 52–60.
  77. McCaig, R. & Bendiak, D. S. ( 1985; ). Yeast handling studies. I. Agitation of stored pitching yeast. J Am Soc Brew Chem 43, 114-118.
    [Google Scholar]
  78. Miguel, J. & Fleming, J. ( 1986; ). Theoretical and experimental support for an oxygen radical-mitochondrial injury hypothesis of cell aging. In Free Radicals, Aging and Degenerative Diseases, pp. 51-74. Edited by J. E. Johnson, D. Harman, R. Walford & J. Miguel. New York: Liss.
  79. Mitchison, J. M. (1971). The Biology of the Cell Cycle. London: Cambridge University Press.
  80. Monch, D., Krugwer, E. & Stahl, U. ( 1995; ). Effects of stress on brewery yeasts. Monatsschr Brau 48, 288-299.
    [Google Scholar]
  81. Mortimer, R. K. & Johnston, J. R. ( 1959; ). Life span of individual yeast cells. Nature 183, 1751-1752.[CrossRef]
    [Google Scholar]
  82. Motizuki, M. & Tsurugi, K. ( 1992; ). The effect of aging on protein synthesis in the yeast Saccharomyces cerevisiae. Mech Ageing Dev 64, 235-245.[CrossRef]
    [Google Scholar]
  83. Muller, I. ( 1971; ). Experiments on ageing in single cells of Saccharomyces cerevisiae. Arch Mikrobiol 77, 20-25.[CrossRef]
    [Google Scholar]
  84. Muller, I. ( 1985; ). Parental age and the life-span of zygotes of Saccharomyces cerevisiae. Antonie Leeuwenhoek 51, 1-10.[CrossRef]
    [Google Scholar]
  85. Muller, I., Zimmermann, M., Becker, D. & Flomer, M. ( 1980; ). Calender lifespan versus budding lifespan of Saccharomyces cerevisiae. Mech Aging Dev 12, 47-52.[CrossRef]
    [Google Scholar]
  86. Murray, A. ( 1994; ). Cell cycle checkpoints. Curr Opin Cell Biol 6, 872-876.[CrossRef]
    [Google Scholar]
  87. Nohl, H. ( 1993; ). Involvement of free radicals in ageing: a consequence or cause of senescence. Br Med Bull 49, 653-667.
    [Google Scholar]
  88. Nurse, P. ( 1997; ). Regulation of the eukaryotic cell cycle. Eur J Cancer 33, 1002-1004.[CrossRef]
    [Google Scholar]
  89. Nurse, P., Masui, Y. & Hartwell, L. ( 1998; ). Understanding the cell cycle. Nat Med 4, 1103-1106.[CrossRef]
    [Google Scholar]
  90. O’Connell, M. J. & Nurse, P. ( 1994; ). How cells know they are in G1 or G0. Curr Opin Cell Biol 6, 867-871.[CrossRef]
    [Google Scholar]
  91. Oliver, S. G. ( 1996; ). From DNA sequence to biological function. Nature 379, 597-600.[CrossRef]
    [Google Scholar]
  92. Olovnikov, A. M. ( 1973; ). A theory of marginotomy: the incomplete copying of template margin in enzymatic synthesis of polynucleotides and biological significance of the phenomenon. J Theor Biol 41, 181-190.[CrossRef]
    [Google Scholar]
  93. Osiewacz, H. D. ( 1997; ). Genetic regulation of aging. J Mol Med 75, 715-727.[CrossRef]
    [Google Scholar]
  94. Pringle, J. R. & Hartwell, L. H. ( 1981; ). The Saccharomyces cell cycle. In The Molecular Biology of the Yeast Saccharomyces, pp. 97-142. Edited by J. Strathern, E. W. Jones & J. R. Broach. Cold Spring Harbor Laboratory, NY: Cold Spring Harbor Press.
  95. Rhymes, M. R. & Smart, K. A. ( 1996; ). Effect of starvation on the flocculation of ale and lager yeasts. Am Soc Brew Chem 54, 50-56.
    [Google Scholar]
  96. Rose, M. R. ( 1984; ). Laboratory evolution of postponed senescence in Drosophila melanogaster. Evolution 38, 1004-1010.[CrossRef]
    [Google Scholar]
  97. Sando, N., Maeda, M., Endo, T., Oka, R. & Hayashibe, M. ( 1973; ). Induction of meiosis and sporulation in differently aged cells of Saccharomyces cerevisiae. J Gen Appl Microbiol 19, 359-373.[CrossRef]
    [Google Scholar]
  98. Shore, D. ( 1995; ). Silence is golden. Curr Biol 5, 822-825.[CrossRef]
    [Google Scholar]
  99. Sinclair, D. A. & Guarente, L. ( 1997; ). Extrachromosomal rDNA circles – a cause of aging in yeast. Cell 91, 1033-1042.[CrossRef]
    [Google Scholar]
  100. Sinclair, D. A., Mills, K. & Guarente, L. ( 1997; ). Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 277, 1313-1316.[CrossRef]
    [Google Scholar]
  101. Sinclair, D. A., Mills, K. & Guarente, L. ( 1998; ). Molecular mechanisms of yeast aging. Trends Biochem Sci 23, 131-134.[CrossRef]
    [Google Scholar]
  102. Smart, K. A. ( 1999; ). Ageing in brewing yeast. Brew Guardian 128, 19-24.
    [Google Scholar]
  103. Smart, K. A., Boulton, C. A., Hinchcliffe, E. & Molzahn, S. ( 1995; ). Effect of physiological stress on the surface properties of brewing yeast. J Am Soc Brew Chem 53, 33-38.
    [Google Scholar]
  104. Smeal, T., Claus, J., Kennedy, B., Cole, F. & Guarente, L. ( 1996; ). Loss of transcriptional silencing causes sterility in old mother cells of Saccharomyces cerevisiae. Cell 84, 633-642.[CrossRef]
    [Google Scholar]
  105. Smith, J. R. & Pereira-Smith, O. M. ( 1996; ). Replicative senescence – implications for in vivo aging and tumour suppression. Science 273, 63-67.[CrossRef]
    [Google Scholar]
  106. Sohal, R. S. & Weindruch, R. ( 1996; ). Oxidative stress, caloric restriction, and aging. Science 273, 59-63.[CrossRef]
    [Google Scholar]
  107. Stewart, G. ( 1996; ). Yeast performance and management. The Brewer 82, 211.
    [Google Scholar]
  108. Storz, G., Christman, M. F., Sies, H. & Ames, B. N. ( 1987; ). Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium. Proc Natl Acad Sci USA 84, 8917-8921.[CrossRef]
    [Google Scholar]
  109. Sun, J., Kale, S. P., Childress, A. M., Pinswasdi, C. & Jazwinski, S. M. ( 1994; ). Divergent roles of RAS1 and RAS2 in yeast longevity. J Biol Chem 269, 18638-18645.
    [Google Scholar]
  110. Walker, G. M. ( 1998; ). Control of yeast growth and cell division. In Yeast Physiology and Biotechnology, pp. 112-127. Edited by G. M. Walker. Chichester: Wiley.
  111. Wallace, D. C. ( 1992; ). Mitochondrial genetics – a paradigm for aging and degenerative diseases. Science 256, 628-632.[CrossRef]
    [Google Scholar]
  112. Wawryn, J., Krzepilko, A., Myszka, A. & Bilinski, T. ( 1999; ). Deficiency in superoxide dismutase shortens life span of yeast cells. Acta Biochim Pol 46, 249-253.
    [Google Scholar]
  113. Wei, Y. H. ( 1998; ). Oxidative stress and mitochondrial DNA mutations in human aging. Proc Soc Exp Biol Med 217, 53-63.[CrossRef]
    [Google Scholar]
  114. Wei, W., Nurse, P. & Broek, D. ( 1993; ). Yeast cells can enter a quiescent state through G1, S, G2 or M-phase of the cell-cycle. Cancer Res 53, 1867-1870.
    [Google Scholar]
  115. Wei, Y. H., Pang, C. Y., Lee, H. C. & Lu, C. Y. ( 1998; ). Roles of mitochondrial DNA mutation and oxidative damage in human aging. Curr Sci 74, 887-893.
    [Google Scholar]
  116. Weinert, T. A., Kiser, G. L. & Hartwell, L. H. ( 1994; ). Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 8, 652-665.[CrossRef]
    [Google Scholar]
  117. Werner-Washbourne, M., Braun, E., Johnston, G. C. & Singer, R. A. ( 1993; ). Stationary phase in the yeast Saccharomyces cerevisiae. Microbiol Rev 57, 383-401.
    [Google Scholar]
  118. Wheals, A. E. ( 1987; ). Biology of the cell cycle in yeasts. In The Yeasts, vol. 1, Biology of Yeasts, pp. 283-377. Edited by A. H. Rose & J. S. Harrison. London: Academic Press.
  119. Wolff, S. P., Garner, A. & Dean, R. T. ( 1986; ). Free-radicals, lipids and protein degradation. Trends Biochem Sci 11, 27-31.[CrossRef]
    [Google Scholar]
  120. Yakes, F. M. & Van Houten, B. ( 1997; ). Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 94, 514-519.[CrossRef]
    [Google Scholar]
  121. Zakian, V. A. ( 1989; ). Structure and function of telomeres. Annu Rev Genet 23, 579-604.[CrossRef]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-146-5-1023
Loading
/content/journal/micro/10.1099/00221287-146-5-1023
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error