SUMMARY: The cytoplasmically inherited trait in , is recognized by certain defects in the cytochrome system accompanied by a low growth rate. In the presence of the gene, , the growth rate of a strain becomes nearly normal but the defective cytochrome system remains unchanged, as if the defects were being compensated for by an increase in activity of some other enzyme system. When the allele of this gene is replaced by its normal counterpart the character is again fully expressed. The allele, , is apparently without effect on another cytoplasmically inherited character, , similar in its properties to . Nor do the nuclear gene mutants, C115 and C117, also similar in phenotype, appear to respond to . A nuclear gene suppressor of the mutant, C115, restores to normal not only the growth rate but also the cytochrome system of this mutant. No effect of this suppressor on and C117 has been detected.


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  1. Haskins F.A., Tissieres A., Mitchell II.K., Mitchell M.B. 1953; Cytochromes and the succinic acid oxidase system of poky strains of Neuro- spora. J. biol. Chem. 200:819
    [Google Scholar]
  2. Mitchell M.B., Mitchell H.K. 1952a; A case of ‘maternal’ inheritance in Neurospora crassa. . Proc. nat. Acad. Sci., Wash. 38:442
    [Google Scholar]
  3. Mitchell M.B., Mitchell H.K. 1952b; Observations on suppressors in Neurospora. Proc. nat. Acad. Sci., Wash. 38:205
    [Google Scholar]
  4. Mitchell M.B., Mitchell H.K., Tissieres A. 1953; Mendelian and non- Mendelian factors affecting the cytochrome system in Neurospora crassa. . Proc. nat. Acad. Sci., Wash. 39:606
    [Google Scholar]
  5. Tissieres A., Mitchell H.K. 1954; Cytochromes and respiratory activities in some slow growing strains of Neurospora. J.biol. Chem. 208:241
    [Google Scholar]

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