Transcriptional fusions of DNA to the gene were screened for induction, initially by ethanol and then by hydrogen peroxide (HO). Two fusions were identified which were induced late following treatment with sublethal concentrations of HO (100 μM). The promoter was induced 4–5-fold and mapped to 11° while the promoter was induced 20-fold and mapped close to the right of the defective prophage PBSX, at about 120°. The fusion was induced by mitomycin C as well as HO, which correlated with the induction of PBSX by these agents. This was probably not a transcriptional induction, but rather a consequence of the induction of PBSX replication extending into adjacent regions of the chromosome.


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