Mixed-Ligand Complexes of Platinum(II) as Curing Agents for pBR322 and pBR329 (ColE1) Plasmids in Escherichia coli

V. V. Lakshmi; Padma Sridhar; Badar Taqui Khan; H. Polasa

doi:10.1099/00221287-134-7-1977

Mixed-Ligand Complexes of Platinum(II) as Curing Agents for pBR322 and pBR329 (ColE1) Plasmids in Escherichia coli

V. V. Lakshmi, Padma Sridhar, Badar Taqui Khan and H. Polasa
First Published: 01 July 1988 https://doi.org/10.1099/00221287-134-7-1977

Abstract

Summary: The mixed-ligand complexes of platinum(II) [Pt(Gly)(uracil)Cl2], H2O and [Pt(His)(adenine)]-CI.2H2O eliminated multicopy plasmids with the ColE1 origin of replication in Escherichia coli with 100% frequency. However, plasmids of the IncF1, H1 and X groups were totally refractory to these agents under similar conditions.

Received: 25/11/1987
Revised: 26/02/1988
Published Online: 01/07/1988

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Microbiology

Volume 134, Issue 7

Research Article

Free

Mixed-Ligand Complexes of Platinum(II) as Curing Agents for pBR322 and pBR329 (ColE1) Plasmids in Escherichia coli

Abstract

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