1887

Abstract

Summary: Carbon catabolite derepression induced changes in the pool of yeast mRNAs translatable in a protein-synthesizing reticulocyte system. Competition experiments with globin mRNA showed that the mRNA population obtained from derepressed cells possessed a higher translational efficiency than mRNA from repressed cells. The mRNAs that could account for the high translational efficiency of the derepressed mRNA were not detected in cells growing in glucose-rich medium. Analysis of protein synthesis in the presence of 7-methylguanosine 5′-phosphate indicated that the initiation factors recognizing the 5′-terminal structure of capped messengers interacted with lower affinity with the repressed than with some specific derepressed mRNAs.

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/content/journal/micro/10.1099/00221287-133-6-1471
1987-06-01
2019-10-19
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-133-6-1471
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