Summary: A strain of resistant to low concentrations of cadmium (0.25 mM-Cd) adapted to growth in the presence of 3 mM-Cd in a chemically defined medium. This increased resistance was rapidly lost if Cd was omitted from the growth medium. concentrated Cd actively. Mechanisms appeared to exist for expelling cadmium from cells during the lag and exponential phases and for continued growth in the presence of high intracellular Cd concentrations. Cd-resistant cells adapted so as to control both the extent and rate of Cd uptake when compared to control cells.


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