1887

Abstract

A gene encoding OXA-2 -lactamase has been transposed from the R plasmid R1767. This transposable element which was designated Tn2410 encoded sulphonamide and mercury resistance in addition to the gene. It had a size of 18·5 kb and appeared to be flanked by small inverted repeats. Restriction enzyme analysis resulted in a detailed map of Tn2410, which showed a high degree of similarity with the published map of Tn2603, a transposon encoding OXA-1 -lactamase. The ampicillin and sulphonamide resistance genes on Tn2410 were mapped in a cluster on the region between the centre and the right end of the map.

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1983-09-01
2022-01-17
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