Guinea-pig macrophages exerted bactericidal activity against both a virulent and a saprophytic strain of leptospira in the presence of the homologous IgG. Serum complement alone rendered the saprophytic strain susceptible to phagocytosis by the same macrophages.


Article metrics loading...

Loading full text...

Full text loading...



  1. Cinco M., Banfi E., Soranzo M. R. 1981; Studies on the interaction between macrophages and leptospires. Journal of General Microbiology 124:409–413
    [Google Scholar]
  2. Johnson R. C., Harris V. G. 1967; Antileptospiral activity of serum. II. Leptospiral virulent factors. Journal of Bacteriology 93:513–519
    [Google Scholar]
  3. Lachmann P. J., Hobart M. J. 1978; Complement technology. In Handbook of Experimental Immunology, 3rd edn. pp. 12–16 Edited by Weir D. M. Oxford: Blackwell Scientific Publications;
    [Google Scholar]
  4. Petelin N., Cinco M., Magliocchetti-Lombi P. 1970; Comparative diagnostic significance of some water leptospirae for human leptospirosis. Tropical and Geographical Medicine 22:245–249
    [Google Scholar]
  5. Rottini G. D., Cinco M., Panizon F., Agosti E. 1972; Comportamento delle Ig seriche nell’uomo dopo vaccinazione con leptospira saprofita (ceppo Patoc 1). Giornale di malattie infettive e parassitarie 24:879–885
    [Google Scholar]

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error