1887

Abstract

AM1 grows on 1,2-propanediol with a mean doubling time of 7 h. The growth responses of a wide range of mutants suggest that propanediol is assimilated into cell material by way of pyruvate and acetyl-CoA. The normal enzymes for the initial metabolism of propanediol [NAD(P)-linked dehydrogenase, propanediol oxidase and propanediol dehydratase] were absent. The initial oxidation of propanediol was catalysed by methanol dehydrogenase but only in the presence of a large molecular weight (possibly protein) stimulatory factor that seemed to change the substrate specificity of the enzyme; the product of the oxidation was lactate.

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/content/journal/micro/10.1099/00221287-120-1-245
1980-09-01
2021-10-23
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