%0 Journal Article %A Bolbot, J. A. %A Anthony, C. %T The Metabolism of 1,2-Propanediol by the Facultative Methylotroph Pseudomonas AM1 %D 1980 %J Microbiology, %V 120 %N 1 %P 245-254 %@ 1465-2080 %R https://doi.org/10.1099/00221287-120-1-245 %I Microbiology Society, %X Pseudomonas AM1 grows on 1,2-propanediol with a mean doubling time of 7 h. The growth responses of a wide range of mutants suggest that propanediol is assimilated into cell material by way of pyruvate and acetyl-CoA. The normal enzymes for the initial metabolism of propanediol [NAD(P)+-linked dehydrogenase, propanediol oxidase and propanediol dehydratase] were absent. The initial oxidation of propanediol was catalysed by methanol dehydrogenase but only in the presence of a large molecular weight (possibly protein) stimulatory factor that seemed to change the substrate specificity of the enzyme; the product of the oxidation was lactate. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-120-1-245