1887

Abstract

Mutants PAC1 which could grow on -threonine were isolated. These mutants, like the parent strain, synthesized a biosynthetic threonine deaminase, but its apparent value for threonine was higher than that of the enzyme from strain PAC1. These mutants also synthesized an inducible NAD-dependent threonine dehydrogenase, which was not present in the parent strain. No threonine aldolase activity could be detected. The results suggest that the threonine deaminase with lowered affinity for -threonine, together with -threonine dehydrogenase, enabled these mutants to utilize -threonine as the sole source of carbon for growth.

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/content/journal/micro/10.1099/00221287-117-2-539
1980-04-01
2024-10-12
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