1887

Abstract

Summary: Butirosin, an aminoglycoside antibiotic, is produced by B-3312. Experiments using recombined ribosomal and supernatant fractions from this strain and from KM have shown that the ribosomes of both are sensitive to butirosin. The aminoglycoside 3'-phosphotransferase present in modifies butirosin and neomycin but confers resistance only to the former . The phosphotransferase does not modify a detectable amount of extracellular butirosin while mediating resistance to the antibiotic. , however, the enzyme appears to protect against inhibition by butirosin by inactivating the bulk of the antibiotic in the system. An extrachromosomal element of unknown function has been detected in .

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-115-2-385
1979-12-01
2019-12-06
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-115-2-385
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error