1887

Abstract

SUMMARY: Optimal yields of penicillinase were obtained by the continuous addition of penicillin to cultures of certain strains of during their logarithmic growth phase.

Lower yields of enzyme were obtained if the penicillin was added when growth had ceased or to partly grown cultures kept at rest and subsequently shaken.

Partial lysis of the bacteria was accompanied by an increased yield of enzyme, but complete lysis appeared to result in partial destruction.

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/content/journal/micro/10.1099/00221287-1-3-370
1947-09-01
2019-12-08
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