1887

Journal of Medical Microbiology

Volume 56, Issue 8

Investigation of meticillin-resistant in pigs used for research Free

Abstract

Meticillin-resistant (MRSA) was unexpectedly isolated from a pig used for streptozotocin-induced diabetes research. To investigate the possible source of the MRSA isolate, nasal swabs were obtained from the animal herd, and from animal holding rooms, and veterinary and research staff involved in the handling of the animals. Overall, four MRSA isolates were cultured from three pigs and from a clinician/scientist. Two were ST22-MRSA-IV, a human strain type associated with epidemic spread. The other two were ST398-MRSA-V, a strain type associated with pigs. Thus, care should be taken to prevent cross-transmission of MRSA.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): MLST, multilocus sequence typing , MLVA, multilocus variable number tandem repeat analysis , MRSA, meticillin-resistant Staphylococcus aureus and MSSA, meticillin-sensitive Staphylococcus aureus
© SGM
Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.47283-0
2007-08-01
2019-10-19
Loading full text...

Full text loading...

/deliver/fulltext/jmm/56/8/1107.html?itemId=/content/journal/jmm/10.1099/jmm.0.47283-0&mimeType=html&fmt=ahah

References

  1. Armand-Lefevre, L., Ruimy, R. & Andremont, A. ( 2005; ). Clonal comparison of Staphylococcus aureus isolates from healthy pig farmers, human controls and pigs. Emerg Infect Dis 11, 711–714.[CrossRef]
    [Google Scholar]
  2. Chambers, H. F. ( 2001; ). The changing epidemiology of Staphylococcus aureus? Emerg Infect Dis 7, 178–182.[CrossRef]
    [Google Scholar]
  3. Enright, M. C., Day, N. P. J., Davies, C. E., Peacock, S. J. & Spratt, B. ( 2000; ). Multilocus sequence typing for characterization of methicillin-resistant and methicillin susceptible clones of Staphylococcus aureus. J Clin Microbiol 38, 1008–1015.
     [Google Scholar]
  4. Fey, P. D., Salid-Salim, B., Rupp, M. E., Hinrichs, S. H., Boxrud, D. J., Davis, C. C., Kreiswirth, B. N. & Schlievert, P. M. ( 2003; ). Comparative molecular analysis of community- or hospital-acquired methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 47, 196–203.[CrossRef]
    [Google Scholar]
  5. Haddadin, A. S., Fappiano, S. A. & Lipsett, P. A. ( 2002; ). Methicillin resistant Staphylococcus aureus (MRSA) in the intensive care unit. Postgrad Med J 78, 385–392.[CrossRef]
    [Google Scholar]
  6. Hsu, L.-Y., Koh, T. H., Singh, K., Kang, M. L., Kurup, A. & Tan, B. H. ( 2005; ). Dissemination of multisusceptible methicillin-resistant Staphylococcus aureus in Singapore. J Clin Microbiol 43, 2923–2935.[CrossRef]
    [Google Scholar]
  7. Huijsdens, X. W., van Dijke, B. J., Spalburg, E., van Santen-Verheuvel, M. G., Heck, M. E. O. C., Pluister, G. N., Voss, A., Wannet, W. J. B. & de Neeling, A. J. ( 2006; ). Community-acquired MRSA and pig farming. Ann Clin Microbiol Antimicrob 5, 26 [CrossRef]
    [Google Scholar]
  8. Ito, T., Ma, X. X., Takeuchi, F., Okuma, K., Yuzawa, H. & Hiramatsu, K. ( 2004; ). Novel type staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC. Antimicrob Agents Chemother 48, 2637–2651.[CrossRef]
    [Google Scholar]
  9. Jarraud, S., Mougel, C., Thioulouse, J., Lina, G., Meugnier, H., Forey, F., Nesme, X., Etienne, J. & Vandenessch, F. ( 2002; ). Relationship between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles) and human disease. Infect Immun 70, 631–641.[CrossRef]
    [Google Scholar]
  10. Jevons, M. P. ( 1961; ). Celbenin-resistant staphylococci. BMJ i, 124–125.
     [Google Scholar]
  11. Loeffler, A., Boag, A. K., Sung, J., Lindsay, J. A., Guardabassi, L., Dalsgaard, A., Smith, H., Stevens, K. B. & Lloyd, D. H. ( 2005; ). Prevalence of methicillin-resistant Staphyloccocus aureus among staff and pets in a small animal referral hospital in the UK. J Antimicrob Chemother 56, 692–697.[CrossRef]
    [Google Scholar]
  12. NCCLS ( 2005; ). Performance Standards for Antimicrobial Susceptibility Testing, 14th informational supplement, M100-S15. Wayne, PA: National Committee for Clinical Laboratory Standards.
  13. Sabat, A., Krzyszton-Russjan, J., Strzalka, W., Filipek, R., Kosowska, K., Hryniewicz, W., Travis, J. & Potempa, J. ( 2003; ). New method for typing Staphylococcus aureus strains: multiple-locus variable tandem repeat analysis of polymorphism and genetic relationships of clinical isolates. J Clin Microbiol 41, 1801–1804.[CrossRef]
    [Google Scholar]
  14. Voss, A., Loeffen, F., Bakker, J., Klaassen, C. & Wulf, M. ( 2005; ). Methicillin-resistant Staphylococcus aureus in pig farming. Emerg Infect Dis 11, 1965–1966.[CrossRef]
    [Google Scholar]
  15. Weese, J. S., Dacosta, T., Button, L., Goth, K., Ethier, M. & Boehnke, K. ( 2004; ). Isolation of methicillin-resistant Staphylococcus aureus from the environment in a veterinary teaching hospital. J Vet Intern Med 18, 468–470.[CrossRef]
    [Google Scholar]
  16. Weese, J. S., Archaumbault, M., Willey, B. M., Dick, H., Hearn, P., Kreiswirth, B. N., Said-Salim, B., McGeer, A., Lkihoshvay, Y. & other authors ( 2005; ). Methicillin-resistant Staphylococcus aureus in horses and horse personnel, 2000–2002. Emerg Infect Dis 11, 430–435.[CrossRef]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.47283-0
Loading
Investigation of meticillin-resistant Staphylococcus aureus in pigs used for research
J. Med. Microbiol. 56, 1107 (2007); https://doi.org/10.1099/jmm.0.47283-0
/content/journal/jmm/10.1099/jmm.0.47283-0
/content/journal/jmm/10.1099/jmm.0.47283-0
Loading

Data & Media loading...

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error