1887

Abstract

, considered to be a pathogen for dental caries, is known to cause bacteraemia and infective endocarditis. Herein, an unusual case of repeated bacteraemia caused by identified in a 71-year-old male is described. The patient visited Itami City Hospital with the major complaint of a fever, and a subsequent clinical examination led to a diagnosis of possible infective endocarditis without specific vegetation formation around the heart valve. A bacteriological examination of blood taken at the first visit showed the presence of . Antimicrobial treatment was provided, which successfully eliminated the pathogenic bacteria from the blood. However, the patient returned and was hospitalized twice more with a recurrent fever, and was again detected. Analyses of the biological properties of the isolates showed that they possessed cariogenic properties and had a low susceptibility to phagocytosis by human polymorphonuclear leukocytes. Since the patient had Sjögren's syndrome, in which a reduction of saliva secretion is a characteristic feature, a great number of dental caries lesions were identified. The findings indicated that present in those dental caries lesions caused repeated bacteraemia in this case.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.47186-0
2007-07-01
2019-10-17
Loading full text...

Full text loading...

/deliver/fulltext/jmm/56/7/988.html?itemId=/content/journal/jmm/10.1099/jmm.0.47186-0&mimeType=html&fmt=ahah

References

  1. Almstahl, A., Wikstrom, M., Stenberg, I., Jakobsson, A. & Fagerberg-Mohlin, B. ( 2003; ). Oral microbiota associated with hyposalivation of different origins. Oral Microbiol Immunol 18, 1–8.[CrossRef]
    [Google Scholar]
  2. Fujiwara, T., Nakano, K., Kawaguchi, M., Ooshima, T., Sobue, S., Kawabata, S., Nakagawa, I. & Hamada, S. ( 2001; ). Biochemical and genetic characterization of serologically untypable Streptococcus mutans strains isolated from patients with bacteremia. Eur J Oral Sci 109, 330–334.[CrossRef]
    [Google Scholar]
  3. Horii, T., Muramatsu, H. & Iinuma, Y. ( 2005; ). Mechanisms of resistance to fluoroquinolones and carbapenems in Pseudomonas putida. J Antimicrob Chemother 56, 643–647.[CrossRef]
    [Google Scholar]
  4. Hoshino, T., Kawaguchi, M., Shimizu, N., Hoshino, N., Ooshima, T. & Fujiwara, T. ( 2004; ). PCR detection and identification of oral streptococci in saliva samples using gtf genes. Diagn Microbiol Infect Dis 48, 195–199.[CrossRef]
    [Google Scholar]
  5. Kawabata, S. & Hamada, S. ( 1999; ). Studying biofilm formation of mutans streptococci. Methods Enzymol 310, 513–523.
    [Google Scholar]
  6. Matsumoto-Nakano, M., Fujita, K. & Ooshima, T. ( 2007; ). Comparison of glucan-binding proteins in cariogenicity of Streptococcus mutans. Oral Microbiol Immunol 22, 30–35.
    [Google Scholar]
  7. Nakano, K., Nomura, R., Nakagawa, I., Hamada, S. & Ooshima, T. ( 2004; ). Demonstration of Streptococcus mutans with a cell wall polysaccharide specific to a new serotype, k, in the human oral cavity. J Clin Microbiol 42, 198–202.[CrossRef]
    [Google Scholar]
  8. Nomura, R., Nakano, K., Nemoto, H., Fujita, K., Inagaki, S., Takahashi, T., Taniguchi, K., Takeda, M., Yoshioka, H. & other authors ( 2006; ). Isolation and characterization of Streptococcus mutans in heart valve and dental plaque specimens from a patient with infective endocarditis. J Med Microbiol 55, 1135–1140.[CrossRef]
    [Google Scholar]
  9. Poirel, L., Mammeri, H. & Nordmann, P. ( 2004; ). TEM-121, a novel complex mutant of TEM-type beta-lactamase from Enterobacter aerogenes. Antimicrob Agents Chemother 48, 4528–4531.[CrossRef]
    [Google Scholar]
  10. Rosenberg, M., Gutnick, D. & Rosenberg, E. ( 1980; ). Adherence of bacteria to hydrocarbons: a simple method for measuring cell-surface hydrophobicity. FEMS Microbiol Lett 9, 29–33.[CrossRef]
    [Google Scholar]
  11. Rovery, C., Greub, G., Lepidi, H., Casalta, J. P., Habib, G., Collart, F. & Raoult, D. ( 2005; ). PCR detection of bacteria on cardiac valves of patients with treated bacterial endocarditis. J Clin Microbiol 43, 163–167.[CrossRef]
    [Google Scholar]
  12. Seymour, R. A., Lowry, R., Whitworth, J. M. & Martin, M. V. ( 2000; ). Infective endocarditis, dentistry and antibiotic prophylaxis; time for a rethink?. Br Dent J 189, 610–616.[CrossRef]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.47186-0
Loading
/content/journal/jmm/10.1099/jmm.0.47186-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error