1887

Abstract

pneumonia can be difficult to diagnose. Existing laboratory tests all have shortcomings, especially the ability to diagnose all spp. at an early stage. Detection of DNA in serum can be a valuable tool for the diagnosis of Legionnaires' disease (LD). This report describes two patients with LD diagnosed by PCR using serum samples. In addition, quantification of DNA using real-time PCR during the course of illness was carried out. The results obtained mirrored both the clinical condition and C-reactive protein values during the course of the illness. Quantification of DNA in serum using real-time PCR could be a valuable tool to monitor the effects of antimicrobial therapy in patients with LD.

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2006-05-01
2019-11-21
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