1887

Abstract

Coagulase-negative staphylococci (CNS) are the major cause of nosocomial infections. Methicillin-resistant strains are particularly important because they narrow therapeutic options. Detecting methicillin resistance among CNS has been a challenge for years. The objective of this study was to determine the accuracy of an agar screening test (0.6 and 4 μg oxacillin ml), disc diffusion and the automated MicroScan system to characterize methicillin resistance among CNS. One hundred and seventy five strains were analysed: 41.1 % and 59.9 % other species; 69.1 % were -positive. The results showed that the methods have optimal correlation with the detection of gene for , and . However, accuracy of the tests is impaired when less common species are analysed. The only 100 % accurate test was agar screening with 4 μg oxacillin ml.

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2004-12-01
2019-11-12
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