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Abstract

Rosacea is a chronic inflammatory condition that affects the skin of the face and the eyes. The aetiology of rosacea is not clearly established but increasing evidence suggests a potential role for bacteria in the induction of the condition. A role for , originally isolated from within a mite, in the aetiology of the condition has been suggested. The aim of the study was to determine whether a correlation existed between the level of sebum and the density of in the skin of erythematotelangiectatic rosacea patients, and the reactivity of these patients’ sera to proteins of . Serum reactivity to the 62 and 83 kDa proteins was found in 82.6 % (62/75) of the rosacea patients and in 26.9 % (14/52) of controls ( = 0.0016). In the group of rosacea patients whose sera reacted to proteins, the level of sebum was statistically lower than in controls ( = 0.01). The density of on the face of positive rosacea patients was statistically higher than controls ( = 0.0001). Rosacea patients demonstrated increased populations on their faces and reduced sebum levels. Their sera also showed reactivity to proteins, suggesting a potential role for this bacterium in the aetiology of rosacea.

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2014-02-01
2021-10-22
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