1887

Abstract

One hundred and twenty-one isolates of complex were collected from seven Korean hospitals. Species and groups were identified using partial gene sequences and antimicrobial susceptibility testing was performed using a broth microdilution method. Based on partial gene sequences, 118 isolates were identified as belonging to complex, including , , , and . The isolates were further divided into three groups, I to III. groups II and III were clustered into clade A with and ; group I was clustered into clade B with and . For all complex isolates, the resistance rate to trimethoprim/sulfamethoxazole (TMP/SMX) was very high (30.5 %). Antimicrobial resistance rates varied among species or groups of complex. Isolates of clade A showed significantly lower antimicrobial resistance rates than those of clade B; while 25 % of clade A isolates were multidrug resistant, 46 % of clade B isolates were multidrug resistant ( = 0.001). The finding of high antimicrobial resistance rates, particularly to TMP/SMX, among complex isolates from Korea, and the existence of distinct groups among the isolates, with differences in antimicrobial resistance rates, suggests consideration of alternative agents to TMP/SMX to treat infections and indicates the importance of accurate identification for appropriate selection of treatment options.

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2013-05-01
2020-07-07
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