1887

Abstract

To date, two species, and ‘’ (formerly named ‘'), have been identified from the human stomach. In this study, we observed non--shaped bacteria in gastric tissue sections and successfully isolated them by cultivation. Elongated bacteria were isolated from a patient with gastric-mucosa-associated lymphoid-tissue lymphoma who had been diagnosed as -negative by culture, rapid urease test and histopathology in another hospital. The bacteria were grown only on chocolate agar in a CO incubator, appeared more than 10 μm long in histological sections, formed small colonies and showed poor growth in a brain heart infusion broth; these characteristics apparently differed from common clinical isolates of . However, the bacteria were identified as by PCR of the urease gene, 16S rDNA sequencing, protein profile and antigenicity examined by anti- polyclonal antibody. These observations suggest that the strain identified in this study may contribute to the development of gastroduodenal diseases in cases judged as -negative by ordinary methods.

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2004-03-01
2021-01-26
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