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Abstract
This study aimed to evaluate whether the antibiotic fidaxomicin has in vitro activity against Mycobacterium tuberculosis (Mtb). 38 fully drug-sensitive Mtb strains and 34 multidrug-resistant tuberculosis (MDR-TB) strains were tested using the microplate alamar blue assay (MABA) method to determine the minimum inhibitory concentrations (MICs) for fidaxomicin and rifampicin. Fidaxomicin has high in vitro activity against Mtb and is a potential drug to treat Mtb, and MDR-TB infections in particular.
- Received:
- Accepted:
- Published Online:
Funding
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Tongzhou Yunhe Project
(Award YH201917)
- Principle Award Recipient: GuirongWang
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Beijing Talents foundation
(Award 2018000021223)
- Principle Award Recipient: GuirongWang
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National Major Science and Technology Projects of China
(Award 2017ZX10302301-003-004)
- Principle Award Recipient: GuirongWang
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National Major Science and Technology Projects of China
(Award 2017ZX09304009-004)
- Principle Award Recipient: GuirongWang
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National Natural Science Foundation of China
(Award 32070937)
- Principle Award Recipient: HaoLi
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National Natural Science Foundation of China
(Award 81703632)
- Principle Award Recipient: GuirongWang
© 2021 The Authors