1887

Abstract

The standard for surface decontamination is bleach solution at a concentration of 10 % of sodium hypochlorite. Pulsed xenon UV light (PX-UV) is a means of quickly producing germicidal UV that has been shown to be effective in reducing environmental contamination by spores. The purpose of this study was to investigate whether PX-UV was equivalent to bleach for decontamination of surfaces in infection isolation rooms. High-touch surfaces in rooms previously occupied by infected patients were sampled after discharge but before and after cleaning using either bleach or non-bleach cleaning followed by 15 min of PX-UV treatment. A total of 298 samples were collected by using a moistened wipe specifically designed for the removal of spores. Prior to disinfection, the mean contamination level was 2.39 c.f.u. for bleach rooms and 22.97 for UV rooms. After disinfection, the mean level of contamination for bleach was 0.71 c.f.u. ( = 0.1380), and 1.19 c.f.u. ( = 0.0017) for PX-UV disinfected rooms. The difference in final contamination levels between the two cleaning protocols was not significantly different ( = 0.9838). PX-UV disinfection appears to be at least equivalent to bleach in the ability to decrease environmental contamination with spores. Larger studies are needed to validate this conclusion.

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2015-02-01
2019-10-22
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References

  1. Blazejewski C., Guerry M. J., Preau S., Durocher A., Nseir S.. ( 2011;). New methods to clean ICU rooms. . Infect Disord Drug Targets 11:, 365–375. [CrossRef][PubMed]
    [Google Scholar]
  2. Boyce J. M., Havill N. L., Otter J. A., McDonald L. C., Adams N. M., Cooper T., Thompson A., Wiggs L., Killgore G. et al. ( 2008;). Impact of hydrogen peroxide vapor room decontamination on Clostridium . difficile environmental contamination and transmission in a healthcare setting. Infect Control Hosp Epidemiol 29:, 723–729. [CrossRef][PubMed]
    [Google Scholar]
  3. Carrico R. M., Bryant K., Lessa F., Limbago B., Fauerbach L. L., Marx J. F., Sands F., Stephens D., Westhusing K., Wiemken T.. ( 2013;). Guide to Preventing Clostridium Difficile Infections. Washington, DC:: Association for Professionals in Infection Control and Epidemiology (APIC);.
    [Google Scholar]
  4. Cohen S. H., Gerding D. N., Johnson S., Kelly C. P., Loo V. G., McDonald L. C., Pepin J., Wilcox M. H..Society for Healthcare Epidemiology of AmericaInfectious Diseases Society of America ( 2010;). Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). . Infect Control Hosp Epidemiol 31:, 431–455. [CrossRef][PubMed]
    [Google Scholar]
  5. Cristina M. L., Spagnolo A. M., Orlando P., Perdelli F.. ( 2013;). The role of the environment in the spread of emerging pathogens in at-risk hospital wards. . Rev Med Microbiol 24:, 104–112. [CrossRef]
    [Google Scholar]
  6. Doan L., Forrest H., Fakis A., Craig J., Claxton L., Khare M.. ( 2012;). Clinical and cost effectiveness of eight disinfection methods for terminal disinfection of hospital isolation rooms contaminated with Clostridium difficile 027. . J Hosp Infect 82:, 114–121. [CrossRef][PubMed]
    [Google Scholar]
  7. Dubberke E.. ( 2012;). Strategies for prevention of Clostridium difficile infection. . J Hosp Med 7: (Suppl. 3), S14–S17. [CrossRef][PubMed]
    [Google Scholar]
  8. Fraise A.. ( 2011;). Currently available sporicides for use in healthcare, and their limitations. . J Hosp Infect 77:, 210–212. [CrossRef][PubMed]
    [Google Scholar]
  9. Hacek D. M., Ogle A. M., Fisher A., Robicsek A., Peterson L. R.. ( 2010;). Significant impact of terminal room cleaning with bleach on reducing nosocomial Clostridium difficile.. Am J Infect Control 38:, 350–353. [CrossRef][PubMed]
    [Google Scholar]
  10. Levin J., Riley L. S., Parrish C., English D., Ahn S.. ( 2013;). The effect of portable pulsed xenon ultraviolet light after terminal cleaning on hospital-associated Clostridium difficile infection in a community hospital. . Am J Infect Control 41:, 746–748. [CrossRef][PubMed]
    [Google Scholar]
  11. Nerandzic M. M., Cadnum J. L., Pultz M. J., Donskey C. J.. ( 2010;). Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms. . BMC Infect Dis 10:, 197. [CrossRef][PubMed]
    [Google Scholar]
  12. Otter J. A., Puchowicz M., Ryan D., Salkeld J. A., Cooper T. A., Havill N. L., Tuozzo K., Boyce J. M.. ( 2009;). Feasibility of routinely using hydrogen peroxide vapor to decontaminate rooms in a busy United States hospital. . Infect Control Hosp Epidemiol 30:, 574–577. [CrossRef][PubMed]
    [Google Scholar]
  13. Passaretti C. L., Otter J. A., Reich N. G., Myers J., Shepard J., Ross T., Carroll K. C., Lipsett P., Perl T. M.. ( 2013;). An evaluation of environmental decontamination with hydrogen peroxide vapor for reducing the risk of patient acquisition of multidrug-resistant organisms. . Clin Infect Dis 56:, 27–35. [CrossRef][PubMed]
    [Google Scholar]
  14. Qureshi Z., Yassin M. H.. ( 2013;). Role of ultraviolet (UV) disinfection in infection control and environmental cleaning. . Infect Disord Drug Targets 13:, 191–195. [CrossRef][PubMed]
    [Google Scholar]
  15. Rutala W. A., Weber D. J.. ( 2013;). Disinfectants used for environmental disinfection and new room decontamination technology. . Am J Infect Control 41: (Suppl.), S36–S41. [CrossRef][PubMed]
    [Google Scholar]
  16. Rutala W. A., Gergen M. F., Weber D. J.. ( 2010;). Room decontamination with UV radiation. . Infect Control Hosp Epidemiol 31:, 1025–1029. [CrossRef][PubMed]
    [Google Scholar]
  17. Stibich M., Stachowiak J., Tanner B., Berkheiser M., Moore L., Raad I., Chemaly R. F.. ( 2011;). Evaluation of a pulsed-xenon ultraviolet room disinfection device for impact on hospital operations and microbial reduction. . Infect Control Hosp Epidemiol 32:, 286–288. [CrossRef][PubMed]
    [Google Scholar]
  18. Weber D. J., Anderson D. J., Sexton D. J., Rutala W. A.. ( 2013;). Role of the environment in the transmission of Clostridium difficile in health care facilities. . Am J Infect Control 41: (Suppl.), S105–S110. [CrossRef][PubMed]
    [Google Scholar]
  19. Zoutman D., Shannon M., Mandel A.. ( 2011;). Effectiveness of a novel ozone-based system for the rapid high-level disinfection of health care spaces and surfaces. . Am J Infect Control 39:, 873–879. [CrossRef][PubMed]
    [Google Scholar]
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