Twenty colonies from each of 27 randomly selected primary cultures of cholera vibrios on bile-salt agar were investigated. All of the individual colonies comprised cholera vibrios that would be labelled as but they varied in their sensitivity to polymyxin. In 10 of the primary cultures, all of the colonies were of vibrios resistant to polymyxin B, and in another nine cultures all the colonies proved to be of organisms sensitive to the antibiotic. The remaining eight primary cultures were found to be mixtures of sensitive, partially sensitive and resistant colonies. The fact that all the individual colonies in the primary cultures examined were found positive for haemagglutination and resistance to cholera group-TV phage irrespective of their pattern of polymyxin sensitivity indicates that these two characters are not linked with resistance to polymyxin B.


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  1. Barua D. 1970; Laboratory diagnosis of cholera cases and carriers. World Health Organisation Public Health Paper no. 40 Geneva: p 50
    [Google Scholar]
  2. Felsenfeld O. 1966; A review of recent trends in cholera research and control. Bull Wld. Hlth Org 34:161
    [Google Scholar]
  3. Finkelstein R. A., Mukerjee S. 1963; Haemagglutination: a rapid method for differentiating V. cholerae and eltor vibrios. Proc. Soc. exp. Biol. Med 112:355
    [Google Scholar]
  4. Han G. K., Khie T. S. 1963; A new method for the differentiation of V. comma and V. eltor. Am. J. Hyg 77:184
    [Google Scholar]
  5. Mukerjee S. 1963; The bacteriophage susceptibility test in differentiating Vibrio cholerae and Vibrio eltor. Bull. Wld Hlth Org 28:333
    [Google Scholar]
  6. Pal S. C., Gugnani H. C., Misra B. S., Shrivastav J. B. 1973; Variants of Vibrio cholerae in Delhi. Indian J. med. Res 61:649
    [Google Scholar]
  7. Roy C., Mridha K., Mukerjee S. 1965; Action of polymyxin on cholera vibrios: techniques of determination of polymyxin-sensitivity. Proc. Soc. exp. Biol. Med 119:893
    [Google Scholar]

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