1887

Abstract

SUMMARY

Different R factors were transferred from R  to two strains of in the alimentary tractof chicks. The virulence of the R  strains was then compared with the R strains from which they were derived by giving them orally to groups of 1-day-old chicks.

The mortality rates from infection with the R strains were similar to, slightly lower than, or much lower than those from infection with the corresponding R strains.

Virulence tests on strains from which R factors had been eliminated, and on strains to which R factors had been transferred at a high rate , suggested that the very possession of R factors was responsible for the smaller reductions in mortality rate observed with some of the R strains; but the other strains with which greatly reduced mortality rates were observed may have been low-virulence variants of the R parent strain that had subsequently acquired R factors from the R .

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/content/journal/jmm/10.1099/00222615-5-4-451
1972-11-01
2024-10-14
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References

  1. Anderson E. S. 1965; A rapid screening test for transfer factors in drug-sensitive Entero- bacteriaceae. Nature, Lond 208:1016
    [Google Scholar]
  2. Bouanchaud D. H., Scavizzi M. R., Chabbert Y. A. 1968; Elimination by ethidium bromide of antibiotic resistance in enterobacteria and staphylococci. J. Gen. Microbiol 54:417
    [Google Scholar]
  3. Felix A., Callow Bessie R. 1943; Typing of paratyphoid B bacilli by means of Vi bacteriophage. Br. Med. J 2:127
    [Google Scholar]
  4. Hirota Y. 1960; The effect of acridine dyes on mating typefactors in Escherichia coli. Proc. Natn. Acad. Sei. USA 46:57
    [Google Scholar]
  5. Kay D. 1962; The nucleic acid composition of bacteriophage. J. Gen. Microbiol 27:201
    [Google Scholar]
  6. Smith H. W. 1970; The transfer of antibiotic resistance between strains of enterobacteria in chickens, calves and pigs. J. Med. Microbiol 3:165
    [Google Scholar]
  7. Smith H. W., Linggood Margaret A. 1970; Transfer factors in Escherichia coli with particular regard to their incidence in enteropathogenic strains. J.Gen. Microbiol 62:287
    [Google Scholar]
  8. Thiele Elizabeth H. 1970; Virulence of R-factor-bearing Salmonella typhimurium. Infect.Immun. 2:516
    [Google Scholar]
  9. Watanabe T. 1971; Transferable antibiotic resistance in enterobacteriaceae: relationship to the problems of treatment and control of coliform enteritis. Ann. N. Y. Acad. Sei 176:371
    [Google Scholar]
  10. Watanabe T., Watanabe M. 1969; Episomic resistance factors in Enterobacteriaceae: 38. Virulence for mice of Salmonella typhimurium LT-2 carrying various R factors. Igaku to Seibutsugaku 79:139 (in Japanese)
    [Google Scholar]
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