1887

Abstract

During the period 1979–1991, Typhimurium DT 204c was the cause of a major epidemic of salmonellosis in calves in the UK. Plasmid profile analysis of DT 204c isolates from England and Wales commenced in 1986 and isolates from all subsequent incidents were examined by this technique. Forty-three different plasmid profile types (PPTs) were detected, of which the commonest, designated type E, constituted 44.6–80.2% of the annual incidents during the study period. Some PPTs, e.g., F and P, were detected throughout most years of the study, whereas PPTs O and 6 persisted for short periods. Until 1984, most isolates were resistant to neomycin, but the subsequent predominant PP type E was sensitive to this antibacterial agent. It was concluded that during the epidemic there was an evolution of new genotypes, of which only some persisted; again, antibacterial resistance genes may be acquired or lost. The study demonstrated the value of PP typing for epidemiological studies.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-47-6-483
1998-06-01
2022-01-23
Loading full text...

Full text loading...

/deliver/fulltext/jmm/47/6/medmicro-47-6-483.html?itemId=/content/journal/jmm/10.1099/00222615-47-6-483&mimeType=html&fmt=ahah

References

  1. Threlfall E. J., Ward L. R., Ashley A. S., Rowe B. Plasmid-encoded trimethoprim resistance in multiresistant epidemic Salmonella typhimurium phage types 204 and 193 in Britain. BMJ 1980; 280:1210–1211
    [Google Scholar]
  2. Willshaw G. A., Threlfall E. J., Ward L. R., Ashley A. S., Rowe B. Plasmid studies of drug-resistant epidemic strains of Salmonella typhimurium belonging to phage types 204 and 193. J Antimicrob Chemother 1980; 6:763–773
    [Google Scholar]
  3. Threlfall E. J., Ward L. R., Rowe B. The use of phage typing and plasmid characterization in studying the epidemiology of multiresistant Salmonella typhimurium. In Russell A. P., Quesnel L. B. (eds) Antibiotics: methods of assessing antimicrobial resistance and the occurrence of resistance. SAB Technical Series London: Academic Press; 1983285–297
    [Google Scholar]
  4. Threlfall E. J., Rowe B., Ferguson J. L., Ward L. R. Characterization of plasmids conferring resistance to gentamicin and apramycin in strains of Salmonella typhimurium phage type 204c isolated in Britain. J Hyg 1986; 97:419–426
    [Google Scholar]
  5. Wray C., McLaren I., Parkinson N. M., Beedell Y. Differentiation of Salmonella typhimurium DT204c by plasmid profile and biotyping. Vet Rec 1987; 121:514–516
    [Google Scholar]
  6. Wray C., Todd N., McLaren I., Beedell Y., Rowe B. The epidemiology of salmonella infection in calves: the role of dealers. Epidemiol Infect 1990; 105:295–305
    [Google Scholar]
  7. McLaren I. M., Wray C. Epidemiology of Salmonella typhimurium infection in calves: persistence of salmonellae on calf units. Vet Rec 1991; 129:461–462
    [Google Scholar]
  8. Wray C., Beedell Y. E., McLaren I. M. A survey of antimicrobial resistance in salmonellae isolated from animals in England and Wales during 1984-1987. Br Vet J 1991; 147:356–369
    [Google Scholar]
  9. Wray C., Todd J. N., Hinton M. Epidemiology of Salmonella typhimurium infection in calves: excretion of S. typhimurium in the faeces of calves in different management systems. Vet Rec 1987; 121:293–296
    [Google Scholar]
  10. Wray C., Todd N., McLaren I. M., Beedell Y. E. The epidemiology of salmonella in calves: the role of markets and vehicles. Epidemiol Infect 1991; 107:521–525
    [Google Scholar]
  11. Wray C., Sojka W. J. Reviews of the progress of dairy science: bovine salmonellosis. J Dairy Sci 1977; 44:383–425
    [Google Scholar]
  12. Woodward M. J., McLaren I., Wray C. Genetic evidence for a chromosomally integrated multiresistance plasmid in Salmonella dublin. J Med Microbiol 1989; 28:205–210
    [Google Scholar]
  13. Threlfall E. J., Frost J. A., Ward L. R., Rowe B. Epidemic in cattle and humans of S. typhimurium DT 104 with chromosomally integrated multiple drug resistance. Vet Rec 1994; 134:577
    [Google Scholar]
  14. Wall P. G., Morgan D., Lamden K. A case control study of infection with an epidemic strain of multiresistant Salmonella typhimurium DT 104 in England and Wales. Commun Dis Rep CDR Review 1994; 4:R130–R135
    [Google Scholar]
  15. Anon Salmonella in Animal and Poultry Production 1992. Ministry of Agriculture, Fisheries and Food, Welsh Office, Agriculture Department, Scottish Office, Agriculture and Fisheries Department; 1993
    [Google Scholar]
  16. Wray C., Davies R. H. A veterinary view of salmonella in farm animals. PHLS Microbiol Digest 1996; 13:44–48
    [Google Scholar]
  17. Smith H. W., Parsell Z. Transmissible substrate-utilizing ability in enterobacteria. J Gen Microbiol 1975; 87:129–140
    [Google Scholar]
  18. Smith H. W. A search for transmissible pathogenic characters in invasive strains of Escherichia coli: the discovery of a plasmid-controlled toxin and a plasmid-controlled lethal character closely associated, or identical, with colicine V. J Gen Microbiol 1974; 83:95–111
    [Google Scholar]
  19. Lang H., Jonson G., Holmgren J., Palva E. T. The maltose regulon of Vibrio cholerae affects production and secretion of virulence factors. Infect Immun 1994; 62:4781–4788
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-47-6-483
Loading
/content/journal/jmm/10.1099/00222615-47-6-483
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error