1887

Abstract

has long been recognised as a heterogeneous group of organisms. The description and identification of two new subgroups, and , in other countries encouraged us to re-examine a collection of isolates from the UK. Of 73 clinical isolates identified as from different parts of England and Wales during 1991–1993, and now subjected to further differentiation tests by the Mycobacterial/Nocardial Reference Laboratory, 15 (20.5%) were identified as based on three out of four characteristics: growth property, acetamide production, rhamnose assimilation and a distinct antibiogram. No isolates were identified as . A revised identification and susceptibility system has significant clinical and taxonomic implications. Its introduction will improve speciation, identify antibiotic resistance and influence the choice of safer alternative therapy for patients infected with spp. in the UK.

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1998-01-01
2022-11-29
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References

  1. Franklin A. A., McClung N. M. Heterogeneity among N. asteroides strains. J Gen Appl Microbiol 1976; 22:151–159
    [Google Scholar]
  2. Goodfellow M., Lechavalier M. P. Genus Nocardia Trevisan. In Williams S. T., Sharpe M. E., Holt J. G. (eds) Bergey’s Manual of Systematic Bacteriology vol 4 Baltimore: Williams and Wilkins Co; 19892350–2353
    [Google Scholar]
  3. Mishra S. K., Gordon R. E., Barnett D. A. Identification of nocardiae and streptomycetes of medical importance. J Clin Microbiol 1980; 11:728–736
    [Google Scholar]
  4. Wallace R. J., Tsukamura M., Brown B. A. Cefotaxime-resistant Nocardia asteroides strains are isolates of the controversial species Nocardia farcinica. J Clin Microbiol 1990; 28:2726–2732
    [Google Scholar]
  5. Wallace R. J., Brown B. A., Tsukamura M., Brown J. M., Onyi G. O. Clinical and laboratory features of Nocardia nova. J Clin Microbiol 1991; 29:2407–2411
    [Google Scholar]
  6. Wallace R. J., Steele L. C., Sumter G., Smith J. M. Antimicrobial susceptibility patterns of Nocardia asteroides. Antimicrob Agents Chemother 1988; 32:1776–1779
    [Google Scholar]
  7. Williams S. T., Goodfellow M., Alderson G., Wellington E. M., Sneath P. H., Sackin M. J Numerical classification of Strepto-myces and related genera. J Gen Microbiol 1983; 129:1743–1813
    [Google Scholar]
  8. Wallace R. J., Steele L. C. Susceptibility testing of Nocardia species for the clinical laboratory. Diagn Microbiol Infect Dis 1989; 9:155–166
    [Google Scholar]
  9. Philpott-Howard J. Update on human nocardiosis. Rev Med Microbiol 1993; 4:207–214
    [Google Scholar]
  10. Schaal K. P., Lee J. H. Actinomycete infections in humans-a review. Gene 1992; 115:201–211
    [Google Scholar]
  11. Boiron P., Provost F., Chevrier G., Dupont B. Review of nocardial infections in France 1987-1990. Eur J Clin Microbiol Infect Dis 1992; 11:709–714
    [Google Scholar]
  12. Tsukamura M., Ohta M. Nocardia farcinica as a pathogen of lung infection. Microbiol Immunol 1980; 24:237–241
    [Google Scholar]
  13. Miralles G. D. Disseminated Nocardia farcinica infection in an AIDS patient. Eur J Clin Microbiol Infect Dis 1994; 13:497–500
    [Google Scholar]
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