1887

Abstract

Surmmary

To elucidate whether and infections occur to a significant extent in monocytes-macrophages, the human monocytic cell line, U-937, was infected with L or TW-183. Chlamydial DNA and genus-specific antigens of the lipopolysaccharides (LPS) in epitopes of the chlamydial cell wall were detected from L-inoculated monocytes over a period of 150 days after inoculation and from the TW-183-inoculated cells during a period of 14 days. -infected U-937 cells expressed significantly lower levels of CD4, CD45RA, CD11b and CD33 cells, determined by flow cytometry, than control uninoculated cells on the seventh day after inoculation and they expressed a slightly increased level of CD4 cells and lower levels of CD45RA and CD11b cells on the 14th day after inoculation. -infected U-937 cells expressed significantly lower levels of CD4, CD45RA, CD11b and CD33 cells than controls on the seventh day after inoculation and an increased level of CD4 and a lower level of CD45RA cells on the 14th day after inoculation. Unlike infection with L strain, chronic persistent infection with appears not to occur in monocytes-macrophages.

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/content/journal/jmm/10.1099/00222615-42-3-191
1995-03-01
2019-11-18
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-42-3-191
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