1887

Abstract

SUMMARY

Pregnant sows were immunised either actively by injecting a bacterial extract or a killed bacterial suspension prepared from serotype O138 :K81(B), or passively by injecting antiserum or immunoglobulins prepared against an extract of the same organism. Antibodies to this organism were detected in serum from the colostrum-deprived piglets of these sows by means of bactericidal, passive cutaneous anaphylaxis, haemagglutination, and antiglobulin-haemagglutination tests. The evidence suggests that piglets may be passively sensitised as a result of the transfer of maternal antibody and that factors such as the character of the antibody and its fixation in the tissues may influence its detection in piglet serum. These results are discussed in relation to the role of hypersensitivity in the pathogenesis of in the newborn piglet.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-4-4-461
1971-11-01
2024-04-26
Loading full text...

Full text loading...

/deliver/fulltext/jmm/4/4/medmicro-4-4-461.html?itemId=/content/journal/jmm/10.1099/00222615-4-4-461&mimeType=html&fmt=ahah

References

  1. Brambell F. W. R. 1958; Pre-natal transference of antibodies. Vet. Rec 70:1060
    [Google Scholar]
  2. Buxton A., Thomlinson J. R. 1961; The detection of tissue-sensitizing antibodies to. Res. Vet. Sci 2:73
    [Google Scholar]
  3. Erskine R. G., Sojka W. J., Lloyd M. K. 1957; The experimental reproduction of a syndrome indistinguishable from oedema disease. Vet. Rec 69:301
    [Google Scholar]
  4. Humphrey J. H., White K. G. 1964; Immunology for students of medicine. 2nd ed Oxford: p 201
    [Google Scholar]
  5. Kim Y. B., Bradley S. G., Watson D. W. 1966; Ontogeny of the immune response. Development of immunoglobulins in germfree and conventional colostrum-deprived piglets. J. Immun 97:52
    [Google Scholar]
  6. Mcgirr J. L. 1947; Colostral transmission of antibody substances from mother to offspring. Vet. J. 103:345
    [Google Scholar]
  7. Muschel L. H., Treffers H. P. 1956; Quantitative studies of the bactericidal actions of serum and complement. I. A rapid photometric growth assay for bactericidal activity. J.Immun. 76:1
    [Google Scholar]
  8. Porter P., Hill I. R. 1970; Serological changes in immunoglobulins IgG, IgA and IgM and Escherichia coli antibodies in the young pig. Immunology 18:565
    [Google Scholar]
  9. Shreeve B. J., Thomlinson J. R. 1970a; Hypersensitivity in young piglets: its relation to the pathogenesis of Escherichia coli disease. J. Med. Microbiol 3:377
    [Google Scholar]
  10. Shreeve B. J., Thomlinson J. R. 1970b; Escherichia coli disease in the piglet. A pathological and bacteriological investigation. Br. Vet. J 126:444
    [Google Scholar]
  11. Shreeve B. J., Thomlinson J. R. 1971a; Hypersensitivity of young piglets to Escherichia coli endotoxin. J. Med. Microbiol. 4:307
    [Google Scholar]
  12. Shreeve B. J., Thomlinson J. R. 1971b; Bacteriological and serological studies in preparturient sows. Br. Vet. J 127:57
    [Google Scholar]
  13. Šterzl J., Kostka J., Riha I., MandeL L. 1960; Attempts to determine the formation and character of gamma globulin and of natural and immune antibodies in young pigs reared without colostrum. Folia microbiol., Praha 5:29
    [Google Scholar]
  14. Šterzl J., Pesak V., Kostka J., Jilek M. 1964; The relation between the bactericidal activity of complement and the character of the bacterial surfaces. Folia microbiol., Praha 9:284
    [Google Scholar]
  15. Thomlinson J. R., Buxton A. 1962; A comparison of experimental anaphylactic shock in guinea-pigs with naturally-occurring oedema disease and haemorrhagic gastro-enteritis in pigs. Res. Vet. Sci 3:186
    [Google Scholar]
  16. Thomlinson J. R., Buxton A. 1963; Anaphylaxis in pigs and its relationship to the pathogenesis of oedema disease and gastro-enteritis associated with Escherichia coli. Immunology 6:126
    [Google Scholar]
  17. Vaz N. M., Ovary Z. 1968; Passive anaphylaxis in mice with yG antibodies. I. PCA and RPCA reactions with homologous and heterologous antibodies. J. Immun 100:169
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-4-4-461
Loading
/content/journal/jmm/10.1099/00222615-4-4-461
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error