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Sera were tested for capsular antibody and for bactericidal factor against Haemophilus influenzae type b. The age-distribution of the bactericidal factor corresponded to the known age-distribution of immunity to serious infection with H. influenzae type b, but that of the capsular antibody did not. This finding argues against the belief that the protective antibody to H. influenzae type-b infections is that produced against its capsular antigen.
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