1887

Abstract

A small plasmid of 4.4 kb encoding resistance to streptomycin (Sm) was detected in a multiresistant culture from a piglet with exudative epidermitis. The plasmid-encoded properties were determined by interspecies protoplast transformation experiments. This plasmid was further characterised by restriction endonuclease analysis and a preliminary restriction map was constructed. The plasmid from that conferred streptomycin resistance was designated as pSAI-1. It showed some structural homology with the streptomycin-chloramphenicol resistance plasmid pSK68 from of human origin. The MIC of streptomycin in resistance mediated by pSAI-1 was about 10 times higher than the MICs in resistance mediated by Sm plasmids from human strains.

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/content/journal/jmm/10.1099/00222615-32-3-201
1990-07-01
2019-10-23
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-32-3-201
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