1887

Abstract

Summary

The antibacterial properties of aflatoxin B have been evaluated against antibiotic-resistant clinical isolates of and The inhibition of growth ranged from 11.5 to 60.0% and 4.5 to 18.5% in the strains of and , depending on the extent of drug resistance. Aflatoxin-B binding varied with toxin concentration, the presence of surfactants (Tween-80 or EDTA) as well as with the antibiotic-resistance pattern; binding was maximal in antibioticsensitive strains and least in the most resistant strains. Binding of aflatoxin B, correlated with growth inhibition. Aflatoxin B also caused leakage of cell contents and decrease in inulin uptake, effects which were also concentration dependent.

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1986-09-01
2022-08-13
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