A capsulate staphylococcus designated strain M is described. Apart from the presence of a capsule, this strain has most of the biological properties of typical strains of .

Strain M differs from modal strains of in its colonial morphology, resistance to bacteriophage, greater virulence for mice and failure to clump in plasma. These differences are attributed to the presence of a thick capsule.

Non-capsulate variants, produced by prolonged culture in nutrient broth, were indistinguishable from typical strains of , but reverted to the parent capsulate form when passaged in mice.

Strain M is compared with three heavily capsulate strains previously described, and with staphylococcus strain “Smith”, and the “Smith-like” strains of .

The capsulate strain M has been deposited in the National Collection of Type Cultures (no. 10649).


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