1887

Abstract

Summary

During the long-term study of sore throat caused by group-A streptococci in a village, M-positive members of type 12 disappeared and were replaced by streptococci that appeared to be M-negative variants of the original strain.

The new strain resembled the original M-type-12 streptococcus in possessing the T-antigen of type 12, but further investigation showed that it was not M-negative; it had a hitherto undescribed M-antigen. It also differed from the M-type-12 strain in having the ability to produce opacity in horse serum and in not being lysogenic for a phage active on the indicator strain K56.

A minority-population of the new strain was found in 7 of 11 cultures of the original M-type-12 streptococcus. This is taken as evidence that the new strain has arisen as a variant of the M-type-12 streptococcus.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-2-3-199
1969-08-01
2019-10-15
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-2-3-199
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error