1887

Abstract

SUMMARY

During the long-term study of sore throat caused by group-A streptococci in a village, M-positive members of type 12 disappeared and were replaced by streptococci that appeared to be M-negative variants of the original strain.

The new strain resembled the original M-type-12 streptococcus in possessing the T-antigen of type 12, but further investigation showed that it was not M-negative; it had a hitherto undescribed M-antigen. It also differed from the M-type-12 strain in having the ability to produce opacity in horse serum and in not being lysogenic for a phage active on the indicator strain K56.

A minority-population of the new strain was found in 7 of 11 cultures of the original M-type-12 streptococcus. This is taken as evidence that the new strain has arisen as a variant of the M-type-12 streptococcus.

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1969-08-01
2022-01-26
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References

  1. Curtis S. N., Krause R. M. 1964 J. Exp. Med 120:629
    [Google Scholar]
  2. Gooder H. 1961 J. Gen. Microbiol 25:347
    [Google Scholar]
  3. Goslings W. R. O., Valkenburg H. A., Bots A. W., Lorrier J. C. 1963 New Engl. J. Med. 268:687
    [Google Scholar]
  4. Jevons M., Patricia, John, Madeleine, and Parker M. T. 1966 J. Clin. Path 19:305
    [Google Scholar]
  5. Kjems E. 1958 Acta path, microbiol. scand 44:429
    [Google Scholar]
  6. Köhler W. 1963 Zentbl. Bakt. ParasitKde Abt. I, Orig 189:275
    [Google Scholar]
  7. Krumweide Elma. 1954 J. Exp. Med 100:629
    [Google Scholar]
  8. Kuttner Ann G., Lenert T. F. 1944 J. Clin. Invest 23:151
    [Google Scholar]
  9. Lancefield Rebecca C. 1934 J. Exp. Med 59:441
    [Google Scholar]
  10. Lancefield Rebecca C. 1957 Ibid 106:525
    [Google Scholar]
  11. Lancefield Rebecca C. 1962 J. Immun 89:307
    [Google Scholar]
  12. Maxted W. R., Potter Elizabeth V. 1967 J. Gen. Microbiol 49:119
    [Google Scholar]
  13. Ouchterlony Ö. 1949 Acta path. microbiol. scand 26:507
    [Google Scholar]
  14. Parker M. T., Bassett D. C. J., Maxted W. R., Arneaud J. D. 1968 J. Hyg., Camb 66:657
    [Google Scholar]
  15. Potter Elizabeth V., Moran Ann F., Poon-King T., Earle D. P. 1968 J. Lab. Clin. Med 71:126
    [Google Scholar]
  16. Rosendal Kirsten, Bülow P., Jessen O. 1964 Nature, Lond 204:1222
    [Google Scholar]
  17. Rothbard S., Watson R. F. 1948 J. Exp. Med 87:521
    [Google Scholar]
  18. Rowen R. 1961 Ibid 114:807
    [Google Scholar]
  19. Swift H. F., Wilson Armine T., Lancefield Rebecca C. 1943 Ibid 78:127
    [Google Scholar]
  20. Todd E. W., Lancefield Rebecca C. 1928 Ibid 48:751
    [Google Scholar]
  21. Top F. H. Jr, Wannamaker L. W. 1968a J. Hyg., Camb 66:49
    [Google Scholar]
  22. Top F. H., Wannamaker L. W. Jr 1968b J. Exp. Med 127:1013
    [Google Scholar]
  23. Top F. H. Jr, Wannamaker L. W., Maxted W. R., Anthony B. F. 1967 Ibid 126:667
    [Google Scholar]
  24. Valkenburg H. A., Goslings W. R. O., Bots A. W., De Moor C. E., Lorrier J. C. 1963 New Engl. J. Med 268:694
    [Google Scholar]
  25. Valkenburg H. A., Haverkorn van Rijsewijk M. J., Goslings W. R. O., De Moor C. E., Maxted W. R. 1967 Proc. Int. Congr. Chemother., Vienna vol. 6:Supplement II p. 17
    [Google Scholar]
  26. De Waart J., Winkler K. C., Grootsen Ca. 1962 Nature, Lond 195:407
    [Google Scholar]
  27. Wannamaker L. W., Denny F. W., Perry W. D., Siegel A. C., Rammelkamp C. H. 1953 Amer. J. Dis. Child 86:347
    [Google Scholar]
  28. Wiley G. G., Wilson Armine T. 1961 J. Exp. Med 113:451
    [Google Scholar]
  29. Willers J. M. N., Alderkamp Geertruida H. J. 1967 J. Gen. Microbiol 49:41
    [Google Scholar]
  30. Williams R. E. O. 1958 Bull. Wld Hlth Org 19:153
    [Google Scholar]
  31. Wormald P. J. 1956 J. Hyg., Camb 54:89
    [Google Scholar]
  32. Zabriskie J. B. 1964 J. Exp. Med 119:761
    [Google Scholar]
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