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Incubation of rabbit serum for 24 hr with cultures of six strains of saprophytic leptospires brought about a large decrease, or the complete disappearance, of the triglycerides in the lipoproteins of the serum and a corresponding increase in the serum’s content of the free fatty acids. The mechanism underlying the associated changes produced in the electrophoretic pattern of the lipoproteins is discussed in relation to the analogous alteration caused by the lipoprotein lipase.
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