1887

Abstract

Summary

Strains of and were examined by immunological methods for their ability to degrade the human serum proteins IgG, IgM, C3 and C5. The proteolytic activity of the strains was measured in terms of the breakdown of serum into trichloroacetic acid-soluble material. Only black-pigmented strains showed proteolytic activity. Strains of degraded IgG, IgM, C3 and C5, strains of IgG and C3, strains of C3 and IgG and a strain of degraded only IgG. These findings are discussed in relation to the pathogenicity of the black-pigmented

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-19-1-85
1985-02-01
2022-08-15
Loading full text...

Full text loading...

/deliver/fulltext/jmm/19/1/medmicro-19-1-85.html?itemId=/content/journal/jmm/10.1099/00222615-19-1-85&mimeType=html&fmt=ahah

References

  1. Carlsson J, Herrmann B F, Höfling J F, Sundqvist G K. 1984; Degradation of the human proteinase inhibitors alpha-1-antitrypsin and alpha-2-macroglobulin by Bacteroides gingivalis. Infection and Immunity 43:644–648
    [Google Scholar]
  2. Carlsson J, Höfling J F, Sundqvist G K. 1984; Degradation of albumin, haemopexin, haptoglobin and transferrin by black-pigmented Bacteroides species. Journal of Medical Microbiology 18:39–46
    [Google Scholar]
  3. Fong J S C, Renaud L. 1978; A hemolytic plate method for alternate-pathway complement activity assay. American Journal of Clinical Pathology 69:156–160
    [Google Scholar]
  4. Ganrot P O. 1972; Crossed immunoelectrophoresis. Scandinavian Journal of Clinical Laboratory Investigation Suppl 124:39–47
    [Google Scholar]
  5. Holdeman L V, Cato E P, Moore W E C. 1977 Anaerobe laboratory manual, 4th. Virginia Polytechnic Institute and State University; Blacksburg VA:144–148
    [Google Scholar]
  6. Ingham H R, Sisson P R, Middleton R L, Narang H K, Codd A A, Selkon J B. 1981; Phagocytosis and killing of bacteria in aerobic and anaerobic conditions. Journal of Medical Microbiology 14:391–399
    [Google Scholar]
  7. Ingham H R, Sisson P R, Tharagonnet D, Selkon J B, Codd A A. 1977; Inhibition of phagocytosis in vitro by obligate anaerobes. Lancet 2:1252–1254
    [Google Scholar]
  8. Jones G R, Gemmell C G. 1982; Impairment by Bacteroides species of opsonisation and phagocytosis of enterobacteria. Journal of Medical Microbiology 15:351–361
    [Google Scholar]
  9. Kilian M. 1981; Degradation of immunoglobulins A1, A2, and G by suspected principal periodontal pathogens. Infection and Immunity 34:757–765
    [Google Scholar]
  10. Kilian M, Mestecky J, Schrohenloher R E. 1979; Pathogenic species of the genus Haemophilus and Streptococcus pneumoniae produce immunoglobulin Al protease. Infection and Immunity 26:143–149
    [Google Scholar]
  11. Lange K. 1962; Über den immunologischen Mechanismus der akuten und der chronischen Glomerulonephritis. Wollheim E. Glomerulare und tubulare Nierenerkrankungen Georg Thieme Verlag; Stuttgart:232–245
    [Google Scholar]
  12. Laurell C-B. 1972; Electroimmuno assay. Scandinavian Journal of Clinical Laboratory Investigation Suppl 124:21–37
    [Google Scholar]
  13. Löfgren S, Tärnvik A, Carlsson J. 1980; Demonstration of opsonizing antibodies to Francisella tularensis by leukocyte chemiluminescence. Infection and Immunity 29:329–334
    [Google Scholar]
  14. MacDonald J B, Socransky S S, Gibbons R J. 1963; Aspects of the pathogenesis of mixed anaerobic infections of mucous membranes. Journal of Dental Research 42: Suppl 529–544
    [Google Scholar]
  15. Male C J. 1979; Immunoglobulin Al protease production by Haemophilus influenzae and Streptococcus pneumoniae. Infection and Immunity 26:254–261
    [Google Scholar]
  16. Mayrand D, McBride B C, Edwards T, Jensen S. 1980; Characterization of Bacteroides asaccharolyticus and B melaninogenicus oral isolates. Canadian Journal of Microbiology 26:1178–1183
    [Google Scholar]
  17. Neidhardt F C, Bloch P L, Smith D F. 1974; Culture medium for enterobacteria. Journal of Bacteriology 119:736–747
    [Google Scholar]
  18. Plaut A G, Gilbert J V, Artenstein M S, Capra J D. 1975; Neisseria gonorrhoeae and Neisseria meningitidis: extracellular enzyme cleaves human immunoglobulin A. Science 190:1103–1105
    [Google Scholar]
  19. Schultz D R, Miller K D. 1974; Elastase of Pseudomonas aeruginosa: Inactivation of complement components and complement-derived chemotactic and phagocytic factors. Infection and Immunity 10:128–135
    [Google Scholar]
  20. Socransky S S, Gibbons R J. 1965; Required role of Bacteroides melaninogenicus in mixed anaerobic infections. Journal of Infectious Disease 115:247–253
    [Google Scholar]
  21. Sundqvist G K, Eckerbom M I, Larsson A P, Sjogren U T. 1979; Capacity of anaerobic bacteria from necrotic dental pulps to induce purulent infections. Infection and Immunity 25:685–693
    [Google Scholar]
  22. Sundqvist G K, Carlsson J, Herrmann B F, Höfling J F, Väätäinen A. 1984; Degradation in vivo of the C3 protein of guinea-pig complement by a pathogenic strain of Bacteroides gingivalis. Scandinavian Journal of Dental Research 92:14–24
    [Google Scholar]
  23. Tofte R W, Peterson P K, Schmeling D, Bracke J, Kim Y, Quie P G. 1980; Opsonization of four Bacteroides species: role of the classical complement pathway and immunoglobulin. Infection and Immunity 27:784–792
    [Google Scholar]
  24. van Steenbergen T J M, Kastelein P, Touw J J A, De Graaff J. 1982; Virulence of black-pigmented Bacteroides strains from periodontal pockets and other sites in experimentally induced skin lesions in mice. Journal of Periodontal Research 17:41–49
    [Google Scholar]
  25. Ward P A, Chapitis J, Conroy M C, Lepow I H. 1973; Generation by bacterial proteinases of leukotactic factors from human serum, and human C3 and C5. The Journal of Immunology 110:1003–1009
    [Google Scholar]
  26. Werner H, Müller H E. 1971; Immunelektrophoretische Untersuchungen über die Einwirkung von Bacteroides-, Fusobacterium-, Leptotrichia- und Spaerophorus-Arten auf menschliche Plasmaproteine. Zentralblatt für Bakteriologie I Abt. Orig. 216:96–113
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-19-1-85
Loading
/content/journal/jmm/10.1099/00222615-19-1-85
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error