1887

Abstract

SUMMARY

The virological course of herpes zoster infection in 42 otherwise normal hosts was studied by virus isolation and antibody titration. Varicella-zoster virus (VZV) was isolated from vesicle fluid from all three patients examined on the first day of the vesicular eruption and from five out of six examined on the second day. The isolation rate fell to one out of six patients on the seventh day of illness and VZV was not isolated from patients at a later stage of the illness. IgG antibodies were detected by IFAMA and ELISA, in sera from all the patients by the end of the first week of illness; IgG antibody titres were highest during the second and the third weeks. IgM antibodies to VZV were detected in sera from six of the 42 patients with herpes zoster after fractionation by ion-exchange chromatography.

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/content/journal/jmm/10.1099/00222615-16-3-303
1983-08-01
2022-01-17
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References

  1. Arvin A. M., Koropchak C. M. 1980; Immunoglobulin M and immunoglobulin G to Varicella-zoster virus measured by solid-phase radioimmunoassay: antibody responses to varicella and herpes zoster infections. Journal of Clinical Microbiology 12:367–374
    [Google Scholar]
  2. Bastian F. O., Rabson A. S., Yee C. L., Tralka T. S. 1974; Herpes virus varicellae isolated from human dorsal root ganglia. Archives of Pathology 97:331–333
    [Google Scholar]
  3. Cevenini R., Donati M., Rumpianesi F. 1981; Elementary bodies as single-antigen in a micro-ELISA test for Chlamydia trachomatis antibodies. Microbiologica 4:347–351
    [Google Scholar]
  4. Gerna G., Cereda P. M., Cattaneo E., Achilli G., Gerna M. T. 1979; Antibody to early antigens of Varicella-zoster virus during varicella and zoster. Journal of Infectious Diseases 140:33–41
    [Google Scholar]
  5. Gold E. 1966; Serologic and virus-isolation studies of patients with varicella or herpes-zoster infection. New England Journal of Medicine 274:181–185
    [Google Scholar]
  6. Hacham M., Leventon-Kriss S., Sarov I. 1980; Enzyme-linked immunosorbent assay for detection of virus-specific IgM antibodies to Varicella-zoster virus. Intervirology 13:214–222
    [Google Scholar]
  7. Haikin H., Leventon-Kriss S., Sarov I. 1979; Antibody to Varicella-zoster virus-induced membrane antigen: immunoperoxidase assay with air-dried target cells. Journal of Infectious Diseases 140:601–604
    [Google Scholar]
  8. Johnson M. T., Luby J. P., Buchanan R. A., Mikulec D. 1975; Treatment of Varicella-zoster virus infections with adenine arabinoside. Journal of Infectious Diseases 131:225–229
    [Google Scholar]
  9. Johnson R. B., Libby R. 1980; Separation of immunoglobulin M (IgM) essentially free of IgG from serum for use in systems requiring assay of IgM-type antibodies without interference from rheumatoid factor. Journal of Clinical Microbiology 12:451–454
    [Google Scholar]
  10. Joncas J. H. 1979; Persistence, reactivation and cell transformation by human herpes viruses: Herpes simplex, 1, 2 (HSV-1, HSV-2), Cytomegalovirus (CMV), Varicella-zoster (VZV), Epstein-Barr virus (EBV). Canadian Journal of Microbiology 25:254–260
    [Google Scholar]
  11. Leventon-Kriss S., Yoffe R., Rannon L., Modan M. 1978; Seroepidemiologic aspects of Varicella-zoster virus infections in an Israeli Jewish population. Israel Journal of Medical Sciences 14:766–770
    [Google Scholar]
  12. Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. 1951; Protein measurement with Folin phenol reagent. Journal of Biological Chemistry 193:265–275
    [Google Scholar]
  13. Nikoskelainen J., Hanninen P. 1975; Antibody response to Epstein-Barr virus in infectious mononucleosis. Infection and Immunity 11:42–51
    [Google Scholar]
  14. Ross C. A. C., McDaid R. 1972; Specific IgM antibody in serum of patients with herpes zoster infections. British Medical Journal 4:522–523
    [Google Scholar]
  15. Schimpff S., Serpick A., Stoler B., Rumack H., Mellin J. M., Block J. 1972; Varicella-zoster infection in patients with cancer. Annals of Internal Medicine 76:241–254
    [Google Scholar]
  16. Schmidt N. J., Lennette E. H. 1975; Neutralizing antibody responses to Varicella-zoster virus. Infection and Immunity 12:606–613
    [Google Scholar]
  17. Shirodaria P. V., Fraser K. B., Stanford F. 1973; Secondary fluorescent staining of virus antigens by rheumatoid factor and fluorescein-conjugated anti IgM. Annals of the Rheumatic Diseases 32:53–57
    [Google Scholar]
  18. Tedder R.S., Mortimer P. P., Lord R. B. 1981; Detection of antibody to Varicella-zoster virus by competitive and IgM-antibody capture immunoassay. Journal of Medical Virology 8:89–101
    [Google Scholar]
  19. Whitley R. J., Ch’ien L. T., Dolin R., Galasso G. J., Alford C. A. The Collaborative Study Group 1976; Adenine arabinoside therapy of herpes zoster in immunosuppressed. NIAID collaborative antiviral study. New England Journal of Medicine 294:1193–1199
    [Google Scholar]
  20. Williams V., Gershon A., Brunell P. A. 1974; Serologic response to Varicella-zoster membrane antigens measured by indirect immunofluorescence. Journal of Infectious Diseases 130:669–672
    [Google Scholar]
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