1887

Abstract

Summary.

Trace element and phosphate requirements for the synthesis of vascular-permeability factor (PF) by strains B1307 and VC12 were investigated. While magnesium appeared to be indispensable for strain VC12, small amounts of PF were synthesised by strain B1307 in the presence of iron, zinc and manganese. However, even in the latter strain, maximum synthesis was recorded only in magnesium-containing media. Phosphates in the range 0·75–6·00m controlled the synthesis of PF by both strains.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-14-3-243
1981-08-01
2022-09-30
Loading full text...

Full text loading...

/deliver/fulltext/jmm/14/3/medmicro-14-3-243.html?itemId=/content/journal/jmm/10.1099/00222615-14-3-243&mimeType=html&fmt=ahah

References

  1. Brenner M., Niederwieser A., Pataki G. 1969; Amino acids and derivatives. In Thin layer chromatography–a laboratory handbook Stahl E. , 2nd. George Allen and Unwin; London: ch. V 730–751
    [Google Scholar]
  2. Burton R. M. 1957; The determination of glycerol and dihydroxyacetone. In Methods in enzymology III Colowick S. P., Kaplan N. O. Academic Press; London: section I 246–249
    [Google Scholar]
  3. Callahan L. T., Ryder R. C., Richardson S. H. 1971; Biochemistry of Vibrio cholerae virulence. II. Skin permeability factor/cholera enterotoxin production in a chemically defined medium. Infect. Immun 4:611
    [Google Scholar]
  4. Craig J. P. 1965; A permeability factor (toxin) found in cholera stools and culture filtrates and its neutralization by convalescent cholera sera. Nature, Lond 207:614
    [Google Scholar]
  5. Craig J. P. 1971; Cholera toxins. In Microbial toxins IIA Kadis S., Montie T. C., Ajl S. J. Academic Press; London: ch. 5 189–254
    [Google Scholar]
  6. Dafni Z., Ulitzur S., Shilo M. 1972; Influence of light and phosphate on toxin production and growth of Prymnesium parvum. J. gen. Microbiol 70:199
    [Google Scholar]
  7. Demain A. L. 1968; Regulatory mechanisms and industrial production of microbial metabolites. Lloydia 31:395
    [Google Scholar]
  8. Demain A. L., Inamine E. 1970; Biochemistry and regulation of streptomycin and mannosidostreptomycinase (α-D-mannosidase) formation. Bact. Rev 34:1
    [Google Scholar]
  9. Drew S. W., Demain A. L. 1977; Effect of primary metabolites on secondary metabolism. Ann. Rev. Microbiol 31:343
    [Google Scholar]
  10. Evans D. J., Richardson S. H. 1968; In vitro production of choleragen and vascular permeability factor by Vibrio cholerae. J. Bact 96:126
    [Google Scholar]
  11. Kato I. 1970; Relationship of bacterial structure and metabolism to toxin production. In Microbial toxins I Ajl S. J., Kadis S., Montie T. C. Academic Press: New York; ch. 12 401–443
    [Google Scholar]
  12. Sagar I. K., Nagesha C. N., Bhat J. V. 1979; Effect of metal ions on the production of vascular permeability factor by 569 B strain of Vibrio cholerae. Indian J. med. Res 69:18
    [Google Scholar]
  13. Weinberg E. D. 1970; Biosynthesis of secondary metabolites: roles of trace metals. Advanc. microb. Physiol 4:1
    [Google Scholar]
  14. Weinberg E. D. 1972; Infectious diseases influenced by trace element environment. Ann. N.Y. Acad. Sci 199:274
    [Google Scholar]
  15. Weinberg E. D. 1974; Secondary metabolism: control by temperature and inorganic phosphate. Devi, indust. Microbiol 15:70
    [Google Scholar]
  16. Witney F. R., Failla M. L., Weinberg E. D. 1977; Phosphate inhibition of secondary metabolism in Serratia marcescens. Appl. Envir. Microbiol 33:1042
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-14-3-243
Loading
/content/journal/jmm/10.1099/00222615-14-3-243
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error