1887

Abstract

Summary

Variants that had lost some of their antibiotic-resistance determinants were selected from a multiple-antibiotic-resistant strain of

When tested by subcutaneous injection into guinea-pigs, and measured as the number of cocci needed to produce a skin lesion of an arbitrarily chosen diameter, the virulence of strains fell progressively with loss of resistance determinants. When the staphylococci were injected intracutaneously into mice, however, the results were less easy to interpret, but loss of resistance appeared to be associated with a reduction of the slope of the dose-response line.

There was no association between the antibiogram of the strains and their production of certain enzymes and haemolysins.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-12-1-55
1979-02-01
2020-01-29
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-12-1-55
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error