1887

Abstract

SUMMARY

The effects of various treatments on the immune response of chickens to vaccine prepared from strain PI059 were investigated. The treatments, given on or before the day of hatching, consisted of surgical bursectomy (SB), hormonal bursectomy (HB), surgical thymectomy (ST) and X-irradiation (X).

In chickens subjected to SB, SBX or HB before vaccination, the production of agglutinin and immunoglobulin was impaired, but the production of resistance against challenge was not. In chickens subjected to ST or STX before vaccination, the production of agglutinin and immunoglobulin was unimpaired, but the production of resistance against challenge was diminished. Protection was therefore thymus-dependent.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-11-3-281
1978-08-01
2022-07-04
Loading full text...

Full text loading...

/deliver/fulltext/jmm/11/3/medmicro-11-3-281.html?itemId=/content/journal/jmm/10.1099/00222615-11-3-281&mimeType=html&fmt=ahah

References

  1. Alexander A. M., Soltys M. A. 1973; Relationship of serum agglutinins to protective immunity produced in turkeys immunised against fowl cholera. J. comp. Path 83:191
    [Google Scholar]
  2. Ando T., Baba T. 1969; Studies on the host resistance against Pasteurella multocida; humoral resistance. Jap. J. vet. Sci. Suppl 31:26
    [Google Scholar]
  3. Baba T. 1975; Thymectomy of chicks. In Methods of experimental immunology (IV), Japanese Society for Immunology. Kanazawa p 1081
    [Google Scholar]
  4. Baba T. 1977; Immunogenic activity of a ribosomal fraction obtained from Pasteurella multocida. Infect. Immun. 15:1
    [Google Scholar]
  5. Brownell J. R., Sadler W. W., Fanelli M. J. 1970; Role of bursa of Fabricius in chicken resistance to Salmonella typhimurium. Avian Dis. 14:142
    [Google Scholar]
  6. Chang T. S., Rheins M. S., Winter A. R. 1959; The significance of the bursa of Fabricius of chickens in antibody production. Part III. Resistance to Salmonella typhimurium infection. Poult. Sci 38:174
    [Google Scholar]
  7. Cheville N. F., Richards W. D. 1971; The influence of thymic and bursal lymphoid systems in avian tuberculosis. Am. J. Path 64:97
    [Google Scholar]
  8. Davis B. J. 1964; Disc electrophoresis. II. Method and application to human serum proteins. Ann. N.Y. Acad. Sci 121:404
    [Google Scholar]
  9. George M., Vaughan J. H. 1962; In vitro cell migration as a model for delayed hypersensitivity. Proc. Soc. exp. Biol. Med 111:514
    [Google Scholar]
  10. Heddleston K. L., Gallagher J. E., Rebers P. A. 1970; Fowl cholera; immune response in turkeys. Avian Dis 14:626
    [Google Scholar]
  11. Heddleston K. L., Rebers P. A., Ritchie A. E. 1966; Immunizing and toxic properties of particulate antigens from two immunogenic types of Pasteurella multocida of avian origin. J. Immun 96:124
    [Google Scholar]
  12. Morita C., Soekawa M. 1972; Effect of sinectomy and bursectomy on migration inhibition test of splenic cells in chickens. Poult. Sci 51:1133
    [Google Scholar]
  13. Nakamura T., Hashimoto H. 1968; Effects of Salmonella senftenberg injection on chicks hatched from eggs in treatment of testosterone propionate. J. Fac. fish anim. Husb., Hiroshima Univ. 7:217
    [Google Scholar]
  14. Namioka S., Murata M. 1961; Serological studies on Pasteurella multocida. II. Characteristics of somatic (O) antigen of the organism. Cornell Vet 51:507
    [Google Scholar]
  15. Okuyama S. 1967; Immune response of bursectomized and thymectomized chickens. Saishin-Igaku 22:1965
    [Google Scholar]
  16. Ornstein L. 1964; Disc electrophoresis. I. Background and theory. Ann. N.Y. Acad. Sci 121:321
    [Google Scholar]
  17. Panigrahi D., Panigrahi A. H., Fauser I. S., Mallmann V. H., Waxler G. L. 1972; Effect of thymectomy, thymectomy and X-irradiation, and X-irradiation alone on experimentally induced tuberculosis in the chicken. Am. J. vet. Res 33:1857
    [Google Scholar]
  18. Perek M., Drill A. E. 1962; The role of the bursa of Fabricius in developing immunity in chickens treated with Salmonella typhimurium and Spirochaetagallinarum. Br. vet. J. 118:390
    [Google Scholar]
  19. Sadler R., Edgar S. A. 1969; Importance of the bursa of Fabricius in resistance to disease. 2. Resistance to two bacterial diseases. Poult. Sci 48:1090
    [Google Scholar]
  20. Vardaman T. H., Landreth K., Whatley S., Dreesen L. J., Glick B. 1973; Resistance to Mycoplasma synoviae is bursal dependent. Infect. Immun 8:674
    [Google Scholar]
  21. Yamaguchi Y., Suzuki Y., Uenohara K., Yanagisawa R., Tsukuda I. 1973; The mechanism of cellular immunity in avian tuberculosis. Proc. 3rd A. Meeting Jap. Soc. Immun p 192
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-11-3-281
Loading
/content/journal/jmm/10.1099/00222615-11-3-281
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error