1887

Abstract

Parvoviruses were isolated from and snakes and propagated in viper heart (VH-2) and iguana heart (IgH-2) cells. The full-length genome of a snake parvovirus was cloned and both strands were sequenced. The organization of the 4432-nt-long genome was found to be typical of parvoviruses. This genome was flanked by inverted terminal repeats (ITRs) of 154 nt, containing 122 nt terminal hairpins and contained two large open reading frames, encoding the non-structural and structural proteins. Genes of this new parvovirus were most similar to those from waterfowl parvoviruses and from adeno-associated viruses (AAVs), albeit to a relatively low degree and with some organizational differences. The structure of its ITRs also closely resembled those of AAVs. Based on these data, we propose to classify this virus, the first serpentine parvovirus to be identified, as serpentine adeno-associated virus (SAAV) in the genus .

Loading

Article metrics loading...

/content/journal/jgv/10.1099/vir.0.19616-0
2004-03-01
2024-10-05
Loading full text...

Full text loading...

/deliver/fulltext/jgv/85/3/vir850555.html?itemId=/content/journal/jgv/10.1099/vir.0.19616-0&mimeType=html&fmt=ahah

References

  1. Agbandje-McKenna M., Llamas-Saiz A. L., Wang F., Tattersall P., Rossmann M. G. 1998; Functional implications of the structure of the murine parvovirus, minute virus of mice. Structure 6:1369–1381
    [Google Scholar]
  2. Ahne W., Scheinert P. 1989; Reptilian viruses: isolation of parvovirus-like particles from corn snake Elapha guttata ( Colubridae ). Zentralbl Veterinarmed B 36:409–412
    [Google Scholar]
  3. Benkő M., Harrach B. 2003; Molecular evolution of adenoviruses. Curr Top Microbiol Immunol 272:3–35
    [Google Scholar]
  4. Bergoin M., Tijssen P. 2000; Molecular biology of Densovirinae . Contrib Microbiol 4:12–32
    [Google Scholar]
  5. Berns K. I., Bergoin M., Bloom M., Muzyczka N., Tal J., Tattersall P. 2000; Family Parvoviridae . In Virus Taxonomy . Seventh Report of the International Committee on Taxonomy of Viruses pp  311–323 Edited by van Regenmortel M. H. V., Fauquet C. M, Bishop D. H. L. 8 others San Diego: Academic Press;
    [Google Scholar]
  6. Bossis I., Chiorini J. A. 2003; Cloning of an avian adeno-associated virus (AAAV) and generation of recombinant AAAV particles. J Virol 77:6799–6810
    [Google Scholar]
  7. Brown K. E., Young N. S. 2000; Epidemiology and pathology of erythroviruses. Contrib Microbiol 4:107–122
    [Google Scholar]
  8. Buller R. M., Janik J. E., Sebring E. D., Rose J. A. 1981; Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication. J Virol 40:241–247
    [Google Scholar]
  9. Farkas S. L., Benkő M., Elő P., Ursu K., Dán Á., Ahne W., Harrach B. 2002; Genomic and phylogenetic analyses of an adenovirus isolated from a corn snake ( Elaphe guttata ) imply a common origin with members of the proposed new genus Atadenovirus . J Gen Virol 83:2403–2410
    [Google Scholar]
  10. Fédiere G., Li Y., Zádori Z., Szelei J., Tijssen P. 2002; Genome organization of Casphalia extranea densovirus, a new Iteravirus. Virology 292:299–308
    [Google Scholar]
  11. Girod A., Wobus C. E., Zádori Z., Ried M., Leike K., Tijssen P., Kleinschmidt J. A., Hallek M. 2002; The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity. J Gen Virol 83:973–978
    [Google Scholar]
  12. Heldstab A., Bestetti G. 1984; Virus-associated gastrointestinal diseases in snakes. J Zoo Anim Med 5:118–128
    [Google Scholar]
  13. Hoggan M. D., Shatkin A. J., Blacklow N. R., Koczot F., Rose J. A. 1968; Helper-dependent infectious deoxyribonucleic acid from adenovirus-associated virus. J Virol 2:850–851
    [Google Scholar]
  14. Ilyina T. V., Koonin E. V. 1992; Conserved sequence motifs in the initiator proteins for rolling circle DNA replication encoded by diverse replicons from eubacteria, eucaryotes and archaebacteria. Nucleic Acids Res 20:3279–3285
    [Google Scholar]
  15. Jacobson E. R., Kopit W., Kennedy F. A., Funk R. S. 1996; Coinfection of a bearded dragon, Pogona vitticeps , with adenovirus- and dependo-like viruses. Vet Pathol 33:429–439
    [Google Scholar]
  16. Kim D. Y., Mitchell M. A., Bauer R. W., Poston R., Cho D. Y. 2002; An outbreak of adenoviral infection in inland bearded dragons ( Pogona vitticeps ) coinfected with dependovirus and coccidial protozoa (Isospora sp.). J Vet Diagn Invest 14:332–334
    [Google Scholar]
  17. Koonin E. V. 1993; A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. Nucleic Acids Res 21:2541–2547
    [Google Scholar]
  18. Li Y., Zádori Z., Bando H., Dubuc R., Fédiere G., Szelei J., Tijssen P. 2001; Genome organization of the densovirus from Bombyx mori ( Bm DNV-1) and enzyme activity of its capsid. J Gen Virol 82:2821–2825
    [Google Scholar]
  19. McPherson R. A., Ginsberg H. S., Rose J. A. 1982; Adeno-associated virus helper activity of adenovirus DNA binding protein. J Virol 44:666–673
    [Google Scholar]
  20. Meyers C., Mane M., Kokorina N., Alam S., Hermonat P. L. 2000; Ubiquitous human adeno-associated virus type 2 autonomously replicates in differentiating keratinocytes of a normal skin model. Virology 272:338–346
    [Google Scholar]
  21. Ogawa M., Ahne W., Essbauer S. 1992; Reptilian viruses: adenovirus-like agent isolated from royal python ( Python regius . Zentralbl Veterinarmed B 39:732–736
    [Google Scholar]
  22. Pintel D. J., Gersappe A., Haut D., Pearson J. 1996; Determinants that govern alternative splicing of parvovirus pre-mRNAs. Semin Virol 6:283–290
    [Google Scholar]
  23. Qiu J., Nayak R., Tullis G. E., Pintel D. J. 2002; Characterization of the transcription profile of adeno-associated virus type 5 reveals a number of unique features compared to previously characterized adeno-associated viruses. J Virol 76:12435–12447
    [Google Scholar]
  24. Saraste M., Sibbald P. R., Wittinghofer A. 1990; The P-loop – a common motif in ATP- and GTP-binding proteins. Trends Biochem Sci 15:430–434
    [Google Scholar]
  25. Simpson A. A., Chipman P. R., Baker T. S., Tijssen P., Rossmann M. G. 1998; The structure of an insect parvovirus ( Galleria mellonella densovirus) at 3·7 A resolution. Structure 15:1355–1367
    [Google Scholar]
  26. Simpson A. A., Hebert B., Sullivan G. M., Parrish C. R., Zádori Z., Tijssen P., Rossmann M. G. 2002; The structure of porcine parvovirus: comparison with related viruses. J Mol Biol 315:1189–1198
    [Google Scholar]
  27. Srivastava A., Lusby E. W., Berns K. I. 1983; Nucleotide sequence and organization of the adeno-associated virus 2 genome. J Virol 45:555–564
    [Google Scholar]
  28. Tijssen P., Bergoin M. 1995; Densonucleosis viruses constitute an increasingly diversified subfamily among the parvoviruses. Semin Virol 6:347–355
    [Google Scholar]
  29. Tijssen P., Li Y., El-Far M., Szelei J., Letarte M., Zádori Z. 2003; Organization and expression strategy of the ambisense genome of densonucleosis virus of Galleria mellonella ( Gm DNV). J Virol 77:10357–10365
    [Google Scholar]
  30. Truyen U., Parrish C. R. 2000; Epidemiology and pathology of autonomous parvoviruses. Contrib Microbiol 4:149–162
    [Google Scholar]
  31. Tsao J., Chapman M. S., Agbandje M. 8 other authors 1991; The three-dimensional structure of canine parvovirus and its functional implications. Science 251:1456–1464
    [Google Scholar]
  32. Walz C., Deprez A., Dupressoir T., Durst M., Rabreau M., Schlehofer J. R. 1997; Interaction of human papillomavirus type 16 and adeno-associated virus type 2 co-infecting human cervical epithelium. J Gen Virol 78:1441–1452
    [Google Scholar]
  33. Wozniak E. J., DeNardo D. F., Brewer A., Wong V., Tarara R. P. 2000; Identification of adenovirus- and dependovirus-like agents in an outbreak of fatal gastroenteritis in captive born California mountain kingsnakes, Lampropeltis zonata multicincta . J Herpetol Med Surg 10:4–7
    [Google Scholar]
  34. Xie Q., Bu W., Bhatia S., Hare J., Somasundaram T., Azzi A., Chapman M. S. 2002; The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy. Proc Natl Acad Sci U S A 99:10405–10410
    [Google Scholar]
  35. Zádori Z., Stefancsik R., Rauch T., Kisary J. 1995; Analysis of the complete nucleotide sequences of goose and muscovy duck parvoviruses indicates common ancestral origin with adeno-associated virus 2. Virology 212:562–573
    [Google Scholar]
  36. Zádori Z., Szelei J., Lacoste M. C., Li Y., Gariépy S., Raymond P., Allaire M., Nabi I. R., Tijssen P. 2001; A viral phospholipase A2 is required for parvovirus infectivity. Dev Cell 1:291–302
    [Google Scholar]
/content/journal/jgv/10.1099/vir.0.19616-0
Loading
/content/journal/jgv/10.1099/vir.0.19616-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error