Strong conservation of the constitutive activity of the IE1/2 transcriptional control region in wild-type strains of human cytomegalovirus.

References

1. Arlt H., Lang D., Gebert S., Stamminger T. 1994; Identification of binding sites for the 86-kilodalton IE2 protein of human cytomegalovirus within an IE2-responsive viral early promoter. Journal of Virology 68:4117–4125
   [Google Scholar]
2. Ausubel F., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith J. A., Struhl K. 1989 Current Protocols in Molecular Biology New York: John Wiley;
   [Google Scholar]
3. Boshart M., Weber F., Jahn G., Dorsch-Hasler K., Fleckenstein B., Schaffner W. 1985; A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 41:521–530
   [Google Scholar]
4. Britt W. J., Alford C. A. 1996; Cytomegalovirus. In Fields Virology, 3rd edn. pp 2493–2523 Fields B. N., Knipe D. M., Howley P. M. Edited by Philadelphia: Lippincott-Raven;
   [Google Scholar]
5. Brown J. M., Kaneshima H., Mocarski E. S. 1995; Dramatic interstrain differences in the replication of human cytomegalovirus in SCID-hu mice. Journal of Infectious Diseases 171:1599–1603
   [Google Scholar]
6. Brytting M., Wahlberg J., Lundeberg J., Wahren B., Uhlen M., Sundqvist V. A. 1992; Variations in the cytomegalovirus major immediate-early gene found by direct genomic sequencing. Journal of Clinical Microbiology 30:955–960
   [Google Scholar]
7. Cha T. A., Tom E., Kemble G. W., Duke G. M., Mocarski E. S., Spaete R. R. 1996; Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains. Journal of Virology 70:78–83
   [Google Scholar]
8. Chapman B. S., Thayer R. M., Vincent K. A., Haigwood N. L. 1991; Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells. Nucleic Acids Research 19:3979–3986
   [Google Scholar]
9. Chou S. 1992a; Molecular epidemiology of envelope glycoprotein H of human cytomegalovirus. Journal of Infectious Diseases 166:604–607
   [Google Scholar]
10. Chou S. 1992b; Effect of interstrain variation on diagnostic DNA amplification of the cytomegalovirus major immediate-early gene region. Journal of Clinical Microbiology 30:2307–2310
    [Google Scholar]
11. Chou S. 1992c; Comparative analysis of sequence variation in gp116 and gp55 components of glycoprotein B of human cytomegalovirus. Virology 188:388–390
    [Google Scholar]
12. Chou S. W., Dennison K. M. 1991; Analysis of interstrain variation in cytomegalovirus glycoprotein B sequences encoding neutralization-related epitopes. Journal of Infectious Diseases 163:1229–1234
    [Google Scholar]
13. Fickenscher H., Stamminger T., Rüger R., Fleckenstein B. 1989; The role of a repetitive palindromic sequence element in the human cytomegalovirus major immediate early enhancer. Journal of General Virology 70:107–123
    [Google Scholar]
14. Fleckenstein B., Müller I., Collins J. 1982; Cloning of the complete human cytomegalovirus genome in cosmids. Gene 18:39–46
    [Google Scholar]
15. Fries B. C., Chou S., Boeckh M., Torok Storb B. 1994; Frequency distribution of cytomegalovirus envelope glycoprotein genotypes in bone marrow transplant recipients. Journal of Infectious Diseases 169:769–774
    [Google Scholar]
16. Huang T. H., Oka T., Asai T., Okada T., Merrills B. W., Gertson P. N., Whitson R. H., Itakura K. 1996; Repression by a differentiation-specific factor of the human cytomegalovirus enhancer. Nucleic Acids Research 24:1695–1701
    [Google Scholar]
17. Iskenderian A. C., Huang L., Reilly A., Stenberg R. M., Anders D. G. 1996; Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes. Journal of Virology 70:383–392
    [Google Scholar]
18. Lehner R., Stamminger T., Mach M. 1991; Comparative sequence analysis of human cytomegalovirus strains. Journal ofClinical Microbiology 29:2494–2502
    [Google Scholar]
19. Liu R., Baillie J., Sissons J. G., Sinclair J. H. 1994; The transcription factor YY1 binds to negative regulatory elements in the human cytomegalovirus major immediate early enhancer/promoter and mediates repression in non-permissive cells. Nucleic Acids Research 22:2453–2459
    [Google Scholar]
20. Lubon H., Ghazal P., Hennighausen L., Reynolds-Kohler C., Lockshin C., Nelson J. 1989; Cell-specific activity of the modulator region in the human cytomegalovirus major immediate-early gene. Molecular and Cellular Biology 9:1342–1345
    [Google Scholar]
21. Malone C. L., Vesole D. H., Stinski M. F. 1990; Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins. Journal of Virology 64:1498–1506
    [Google Scholar]
22. Meier J. L., Stinski M. F. 1996; Regulat ion of human cytomegalovirus immediate-early gene expression. Intervirology 39:331–342
    [Google Scholar]
23. Meier J. L., Stinski M. F. 1997; Effect of a modulator deletion on transcription of the human cytomegalovirus major immediate-early genes in infected undifferentiated and differentiated cells. Journal of Virology 71:1246–1255
    [Google Scholar]
24. Mocarski E. S., Kemble G. W., Lyle J. M., Greaves R. F. 1996; A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation. Proceedings of the National Academy of Sciences, USA 93:11321–11326
    [Google Scholar]
25. Nelson J. A., Reynolds-Kohler C., Smith B. A. 1987; Negative and positive regulation by a short segment in the 5⁷-flanking region of the human cytomegalovirus major immediate-early gene. Molecular and Cellular Biology 7:4125–4129
    [Google Scholar]
26. Plotkin S. A., Starr S. E., Friedman H. M., Gonczol E., Weibel R. E. 1989; Protective effects of Towne cytomegalovirus vaccine against low-passage cytomegalovirus administered as a challenge. Journal of Infectious Diseases 159:860–865
    [Google Scholar]
27. Shelbourn S. L., Kothari S. K., Sissons J. G., Sinclair J. H. 1989; Repression of human cytomegalovirus gene expression associated with a novel immediate early regulatory region binding factor. Nucleic Acids Research 17:9165–9171
    [Google Scholar]
28. Sinclair J. H., Baillie J., Bryant L. A., Taylor-Wiedeman J. A., Sissons J. G. P. 1992; Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line. Journal of General Virology 73:433–435
    [Google Scholar]
29. Stamminger T., Puchtler E., Fleckenstein B. 1991; Discordant expression of the immediate-early 1 and 2 gene regions of human cytomegalovirus at early times after infection involves posttranscriptional processing events. Journal of Virology 65:2273–2282
    [Google Scholar]
30. Stinski M. F., Roehr T. J. 1985; Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific trans-acting components. Journal of Virology 55:431–441
    [Google Scholar]
31. Thomsen D. R., Stenberg R. M., Goins W. F., Stinski M. F. 1984; Promoter-regulatory region of the major immediate early gene of human cytomegalovirus. Proceedings of the National Academy of Sciences, USA 81:659–663
    [Google Scholar]
32. Vogelberg C., Meyer Konig U., Hufert F. T., Kirste G., Von Laer D. 1996; Human cytomegalovirus glycoprotein B genotypes in renal transplant recipients. Journal of Medical Virology 50:31–34
    [Google Scholar]
33. Westin G., Gerster T., Muller M. M., Schaffner G., Schaffner W. 1987; OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts. Nucleic Acids Research 15:6787–6798
    [Google Scholar]