1887

Abstract

Small mammals trapped in Sweden were analysed for specific antibody responses against three hantavirus serotypes and for the presence of viral antigen. To determine the genetic identity of viral RNA in lungs of seropositive bank voles (), polymerase chain reactions and subsequent partial sequencing of both the M and S segments were employed. The sequences obtained were all identified as Puumala (PUU) virus, with a high degree of heterogeneity between the different geographical localities. Alignment of nucleotide and deduced amino acid sequences, together with phylogenetic analysis, showed that PUU viruses circulating in central Sweden were distinct from those in the northern region. The localization of the two distinct PUU virus genotypes was shown to correlate with the postglacial recolonization of Sweden by bank voles.

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1996-10-01
2022-05-19
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References

  1. Antic D., Lim B. U., Kang C. Y. 1991; Nucleotide and coding capacity of the large (L) segment of Seoul 80-39 virus, a member of the hantavirus genus. Virus Research 19:59–66
    [Google Scholar]
  2. Brummer-Korvenkontio M. A., Vaheri A., Hovi T., Von Bonsdorff C.-H., Vuorimies J., Manni T., Penttinen K., Oker-Blom N., Lahdevirta J. 1980; Nephropathia epidemica: detection of antigen in bank voles and serologic diagnosis of human infection. Journal of Infectious Diseases 141:131–134
    [Google Scholar]
  3. Chizhikov V., Spiropoulou C. F., Morzunov S., Monroe M. C., Peters C. J., Nichol S. T. 1995; Complete genetic characterization and analysis of isolation of Sin Nombre virus. Journal of Virology 69:8132–8136
    [Google Scholar]
  4. Chomczynski P., Sacchi N. 1987; Single-step of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Annals of Biochemistry 162:156–159
    [Google Scholar]
  5. Chu Y. K., Rossi C., Leduc J. W., Lee H. W., Schmaljohn C. S., Dalrymple J. M. 1994; Serological relationships among vimses in the Hantavirus genus, family Bunyaviridae. Virology 198:196–204
    [Google Scholar]
  6. Dzagurova T., Tkachenko E., Slonova R., Ivanov L., Ivanedze E., Markeshin S., Dekonenko A., Niklasson B., Lundkvist A. 1995; Antigenic relationships of hantavirus strains identified by monoclonal antibodies. Archives of Virology 140:1763–1773
    [Google Scholar]
  7. Elliott R. M. 1990; Molecular biology of the Bunyaviridae. Journal of General Virology 71:501–522
    [Google Scholar]
  8. Felsenstein J. 1993 PHYLIP: Phylogeny interference package, version 3.5c University of Washington; Seattle, Wash., USA:
    [Google Scholar]
  9. Hjelle B., Chavez-Giles F., Torrez-Martinez N., Yates T., Sarisky S., Webb J., Ascher M. 1994; Genetic identification of a novel hantavirus of the harvest mouse Reithrodontomys megalotis . Journal of Virology 68:6751–6754
    [Google Scholar]
  10. Holland J. J. 1992; Genetic diversity of RNA viruses. Current Topics in Microbiology and Immunology 176:
    [Google Scholar]
  11. Hörling J., Lundkvist A., Persson K., Mullaart M., Dzagurova T., Dekonenko A., Tkachenko E., Niklasson B. 1995a; Detection and subsequent sequencing of Puumala vims from human specimens by polymerase chain reaction. Journal of Clinical Microbiology 33:277–282
    [Google Scholar]
  12. Hörling J., Cheng Y., Plyusnin A., Persson K., Lehvaslaiho H., Vaheri A., Niklasson B., Lundkvist A. 1995b; Nucleotide and deduced amino acid sequences of the M and S genome segments of a Swedish Puumala vims isolate. Virus Research 39:321–330
    [Google Scholar]
  13. Hörling J., Chizhikov V., Lundkvist A., Jonsson M., Ivanov L., Dekonenko A., Niklasson B., Dzagurova T., Peters C. J., Tkachenko E., Nichol S. 1996; Khabarovsk vims: a phylogenetically and serologically distinct Hantavirus isolated from Microtus fortis trapped in far-east Russia. Journal of General Virology 77:687–694
    [Google Scholar]
  14. Jaarola M., Tegelstrom H. 1995; Colonization history of north European field voles (Microtus agrestis) revealed by mitochondrial DNA. Molecular Ecology 4:299–310
    [Google Scholar]
  15. Khan A. S., Spiropoulou C. F., Morzunov S., Zaki S., Kohn M., Nawas S., McFarland L., Peters C. J., Nichol S. T. 1995; A fatal illness associated with a new hantavims in Louisiana. Journal of Medical Virology 46:281–286
    [Google Scholar]
  16. Lee H. W., Lee P. W., Johnson K. M. 1978; Isolation of the etiologic agent of Korean Hemorrhagic Fever. Journal of Infectious Diseases 137:298–308
    [Google Scholar]
  17. Li D., Schmaljohn A., Anderson K., Schmaljohn C. 1995; Complete nucleotide sequences of the M and S segment of two hantavims isolates from California: evidence for reassortment in nature among vimses related to hantavims pulmonary syndrome. Virology 206:973–983
    [Google Scholar]
  18. Lundkvist Å., Niklasson B. 1994; Haemorrhagic fever with renal syndrome and other hantavims infections. Reviews in Medical Virology 4:177–184
    [Google Scholar]
  19. Lundkvist Å., Fatouros A., Niklasson B. 1991; Antigenic variation of European haemorrhagic fever with renal syndrome vims strains characterized using bank vole monoclonal antibodies. Journal of General Virology 72:2097–2103
    [Google Scholar]
  20. Lundkvist Å., Horling J., Bjorsten S., Niklasson B. 1995; Sensitive detection of hantavimses by biotin—streptavidin enhanced immunoassays based on bank vole monoclonal antibodies. Journal of Virological Methods 52:75–86
    [Google Scholar]
  21. Morzunov S. P., Feldmann H., Spiropoulou C. F., Semenova V. A., Rollin P. E., Ksiazek T. G., Peters C. J., Nichol S. 1995; A newly recognized vims associated with a fatal case of Hantavims pulmonary syndrome in Louisiana. Journal of Virology 69:1980–1983
    [Google Scholar]
  22. Nichol S. T., Rowe J. E., Fitch W. M. 1993a; Punctuated equilibrium and positive Darwinian evolution in vesicular stomatitis vims. Proceedings of the National Academy of Sciences, USA 90:10424–10428
    [Google Scholar]
  23. Nichol S. T., Spiropoulou C., Morzunov S., Rollin P. E., Ksiazek T. G., Feldmann H., Sanchez A., Childs J., Zaki S., Peters C. J. 1993b; Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. Science 262:914–917
    [Google Scholar]
  24. Niklasson B., Kjellson T. 1988; Detection of nephropathia epidemica (Puumala virus)-specific immunoglobulin M by enzyme-linked immunosorbent assay. Journal of Clinical Microbiology 26:1519–1523
    [Google Scholar]
  25. Niklasson B., LeDuc J. W. 1987; Epidemiology of nephropathia epidemica in Sweden. Journal of Infectious Disease 155:269–276
    [Google Scholar]
  26. Niklasson B., Jonsson M., Lundkvist A., Horling J., Tkachenko E. A. 1991; Comparison of European isolates of virus causing hemorrhagic fever with renal syndrome by a neutralization test. American Journal of Tropical Medicine and Hygiene 45:660–665
    [Google Scholar]
  27. Nuzum E. O., Rossi C. R., Stephenson E. H., Leduc J. W. 1988; Aerosol transmission of Hantaan and related viruses to laboratory rats. American Journal of Tropical Medicine and Hygiene 38:636–640
    [Google Scholar]
  28. Plyusnin A., Vapalahti O., Lankinen H., Lehvaslaiho H., Apekina N., Myasnikov Y., Kallio-Kokko H., Henttonen H., Lundkvist A., Brummer-Korvenkontio M., Gavrilovskaya I., Vaheri A. 1994a; Tula virus: a newly detected hantavirus carried by European common voles. Journal of Virology 68:7833–7839
    [Google Scholar]
  29. Plyusnin A., Vapalahti O., Ufves K., Lehvaslaiho H., Apekina N., Gavrilovskaya I., Blinov V., Vaheri A. 1994b; Sequences of wild Puumala virus genes show a correlation of genetic variation with geographic origin of the strains. Journal of General Virology 75:405–409
    [Google Scholar]
  30. Plyusnin A., Cheng Y., Vapalahti O., Pejcoch M., Unar J., Jelinkova Z., Lehvaslaiho H., Vaheri A. 1995a; Genetic variation in Tula hantaviruses: sequence analysis of the S and M segments of strains from Central Europe. Virus Research 39:237–250
    [Google Scholar]
  31. Plyusnin A., Vapalahti O., Lehvaslaiho H., Apekina N., Mikhailova T., Gavriloskaya I., Laakonen K., Niemimaa J., Henttonen H., Brummer-Korvenkontio M., Vaheri A. 1995b; Genetic variation of wild Puumala virus within the serotype, local rodent populations and individual animals. Virus Research 38:25–41
    [Google Scholar]
  32. Reip A., Haring B., Sibold C., Stohwasser R., Bautz E. K. F., Darai G., Meisel H., Kruger D. 1995; Coding strategy of the M and S genomic segments of a hantavirus representing a new subtype of the Puumala virus serotype. Archives of Virology 140:2011–2026
    [Google Scholar]
  33. Rollin P. E., Ksiazek T. G., Elliott L. H., Ravkov E. V., Martin M. L., Morzunov S., Livingstone W., Monroe M., Glass G., Ruo S., Khan A. S., Childs J. E., Nichol S. T., Peters C. J. 1995; Isolation of Black Creek Canal virus, a new hantavirus from Sigmodon hispidus in Florida. Journal of Medical Virology 46:35–39
    [Google Scholar]
  34. Rowe J. E., St Jeor S. C., Riolo J., Otteson E. W., Monroe M. C., Henderson W. W., Ksiazek T. G., Rollin P. E., Nichol S. T. 1995; Coexistence of several novel hantaviruses in rodents indigenous to North America. Virology 213:122–130
    [Google Scholar]
  35. Sanger F., Nicklen S., Coulson A. R. 1977; DNA sequencing with chain-terminating inhibitors. Proceedings of the National Academy of Sciences, USA 74:5463–5467
    [Google Scholar]
  36. Schmaljohn C. S., Hasty E. S., Dalrymple J. M., LeDuc J. W. 1985; Antigenic and genetic properties in viruses linked to hemorrhagic fever with renal syndrome. Science 227:1041–1044
    [Google Scholar]
  37. Sibold C., Sparr S., Schulz A., Labuda M., Kozuch O., Lysy J., Kruger D., Meisel H. 1995; Genetic characterization of a new hantavirus detected in Microtus arvalis from Slovakia. Virus Genes 10:276–281
    [Google Scholar]
  38. Stenseth N. C. 1985; Geographic distribution of Clethrionomys species. Annales Zoologica Fennice 22:215–219
    [Google Scholar]
  39. Taberlet P., Bouvet J. 1994; Mitochondrial DNA polymorphism, polygeography and conservation genetics of brown bear Ursus ados in Europe. Proceedings of the Royal Society of London B 255:195–200
    [Google Scholar]
  40. Tsai F. 1987; Hemorrhagic fever with renal syndrome: mode of transmission to humans. Laboratory Animal Science 37:428–430
    [Google Scholar]
  41. Tegelstrom H. 1987; Transfer of mitochondrial DNA from the Northern red-backed vole (Clethrionomys rutilus) to the bank vole (C. glareolus). Journal of Molecular Evolution 124:218–227
    [Google Scholar]
  42. Tegelstrom H., Wyoni P.-I., Gelter H., Jaarola M. 1988; Concordant divergence in proteins and mitochondrial DNA between two vole species in the genus Clethrionomys . Biochemical Genetics 26:223–237
    [Google Scholar]
  43. Wilson D. E., Reeder D. A. M. (editors) 1993 Mammal Species of the World 2nd edn Washington & London: Smithsonian Institute;
    [Google Scholar]
  44. Xiao S.-Y., Diglisic G., Avsic-Zupanc T., LeDuc J. W. 1993; Dobrava virus: a new hantavirus as evidenced by comparative sequence analysis. Journal of Medical Virology 39:152–155
    [Google Scholar]
  45. Xiao S. Y., LeDuc J. W., Chu Y. K., Schmaljohn C. S. 1994; Phylogenetic analyses of virus isolates in the genus of Hantavirus, family Bunyaviridae . Virology 198:205–217
    [Google Scholar]
  46. Yanagihara R., Gajdusek D. C. 1988; Hemorrhagic fever with renal syndrome: a historical perspective and review of recent advances. In Handbook on Viral and Rickettsial Hemorrhagic Fevers pp 151–158 Edited by Gear J. H. S. Boca Raton: CRC Press;
    [Google Scholar]
  47. Yanagihara R., Amyx H. L., Gajdusek D. C. 1985; Experimental infection with Puumala virus, the etiological agent of nephropathia epidemica, in bank voles (Clethrionomys glareolus). Journal of Virology 55:34–38
    [Google Scholar]
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