1887

Abstract

SUMMARY

Antigenic relatedness between the virion-associated proteins of caprine arthritis-encephalitis, visna and progressive pneumonia viruses was examined. Antigenic cross-reactivity was assessed by immunoprecipitation of disrupted, radiolabelled virus with goat, sheep and rabbit antisera, followed by resolution of the immunoprecipitation products by SDS-polyacrylamide gel electrophoresis. The results indicate that antigenic cross-reactivity between the caprine and ovine virus isolates involves all of the major virion-associated proteins and glycoproteins. The common antigenic determinants exhibited by virion structural proteins are immunogenic in goats, sheep and rabbits.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-66-6-1233
1985-06-01
2022-01-17
Loading full text...

Full text loading...

/deliver/fulltext/jgv/66/6/JV0660061233.html?itemId=/content/journal/jgv/10.1099/0022-1317-66-6-1233&mimeType=html&fmt=ahah

References

  1. Adams D. S., Klevjer-Anderson P., Carlson J. L., McGuire T. C., Gorham J. R. 1983; Transmission and control of caprine arthritis-encephalitis virus. American Journal of Veterinary Research 44:1670–1675
    [Google Scholar]
  2. Adams D. S., Oliver R. E., Ameghino E., Demartini J. C., Verwoerd D. W., Houwers D. J., Weghela S., Gorham J. R., Hyllseth B., Dawson M., Trigo F. J., McGuire T. C. 1985a; Serologic evidence of caprine arthritis-encephalitis virus infection in eleven of fourteen countries tested. Veterinary Record (in press)
    [Google Scholar]
  3. Adams D. S., Gogolewski R. P., Barbet A. F., Cheevers W. P. 1985b; Identification of caprine arthritis-encephalitis retrovirus proteins in immunodiffusion precipitin lines. Journal of General Virology 66:1139–1143
    [Google Scholar]
  4. Banks K. L., Adams D. S., McGuire T. C., Carlson J. L. 1983; Experimental infection of sheep by caprine arthritis-encephalitis virus and goats by progressive pneumonia virus. American Journal of Veterinary Research 44:2307–2311
    [Google Scholar]
  5. Cheevers W. P., Roberson S. M., Klevjer-Anderson P., Crawford T. B. 1981; Characterization of caprine arthritis-encephalitis virus: a retrovirus of goats. Archives of Virology 67:111–117
    [Google Scholar]
  6. Cheevers W. P., Roberson S. M., McGuire T. C., Petersen R. K., Adams D. S., Gorham J. R. 1984; Genetic relationships between caprine arthritis-encephalitis, visna and progressive pneumonia viruses. In Proceedings of E,. E,. C Conference on Slow Virus Infections of Sheep and Goats and Bovine Leukosis (Edinburgh, 1983)
    [Google Scholar]
  7. Clements J. E., Narayan O. 1981; A physical map of the linear unintegrated DNA of visna virus. Virology 113:412–415
    [Google Scholar]
  8. Clements J. E., Narayan O., Cork L. C. 1980; Biochemical characterization of the virus causing leukoencephalitis and arthritis in goats. Journal of General Virology 50:423–427
    [Google Scholar]
  9. Cork L. C., Narayan O. 1980; The pathogenesis of viral leukoencephalomyelitis-arthritis of goats. I. Persistent viral infection with progressive pathologic changes. Laboratory Investigation 42:596–602
    [Google Scholar]
  10. Cork L. C., Hadlow W. J., Crawford T. B., Gorham J. R., Piper R. C. 1974; Infectious leukoencephalomyelitis of young goats. Journal of Infectious Diseases 129:134–141
    [Google Scholar]
  11. Crawford T. B., Adams D. S., Cheevers W. P., Cork L. C. 1980a; Chronic arthritis in goats caused by a retrovirus. Science 207:997–999
    [Google Scholar]
  12. Crawford T. B., Adams D. S., Sande R. D., Gorham J. R., Henson J. E. 1980b; The connective tissue component of the caprine arthritis-encephalitis syndrome. American Journal of Pathology 100:443–450
    [Google Scholar]
  13. Cutlip R. C., Laird G. A. 1976; Isolation and characterization of a virus associated with progressive pneumonia (maedi) of sheep. American Journal of Veterinary Research 37:1377–1382
    [Google Scholar]
  14. Cutlip R. C., Jackson T. A., Lehmkuhl H. D. 1979; Lesions of ovine progressive pneumonia: interstitial pneumonitis and encephalitis. American Journal of Veterinary Research 40:1370–1374
    [Google Scholar]
  15. Dahlberg J. E., Gaskin J. M., Perk K. 1981; Morphological and immunological comparison of caprine arthritis-encephalitis and ovine progressive pneumonia viruses. Journal of Virology 39:914–919
    [Google Scholar]
  16. Ellis T., Robinson W., Wilcox G. 1983; Characterization, experimental infection and serologic response to caprine retrovirus. Australian Veterinary Journal 60:321–326
    [Google Scholar]
  17. Gazit A., Yaniv A., Dvir M., Perk K., Irving S. G., Dahlberg J. E. 1983; The caprine arthritis-encephalitis virus is a distinct virus within the lentivirus group. Virology 124:192–195
    [Google Scholar]
  18. Harris J. D., Scott J. V., Traynor B., Brahic M., Stowring L., Ventura P., Haase A. T., Peluso R. 1981; Visna virus DNA: discovery of a novel gapped structure. Virology 113:573–583
    [Google Scholar]
  19. Johnson G. C., Barbet A. F., Klevjer-Anderson P., McGuire T. C. 1983; Preferential immune response to virion surface glycoproteins by caprine arthritis-encephalitis virus-infected goats. Infection and Immunity 41:657–665
    [Google Scholar]
  20. Klevjer-Anderson P., Cheevers W. P. 1981; Characterization of the infection of caprine synovial membrane cells by the retrovirus caprine arthritis-encephalitis virus. Virology 110:113–119
    [Google Scholar]
  21. Klevjer-Anderson P., McGuire T. C. 1982; Neutralizing antibody response of rabbits and goats to caprine arthritis-encephalitis virus. Infection and Immunity 38:455–461
    [Google Scholar]
  22. Narayan O., Clements J. E., Strandberg J. D., Cork L. C., Griffin D. E. 1980; Biological characterization of the virus causing leukoencephalomyelitis and arthritis in goats. Journal of General Virology 41:343–352
    [Google Scholar]
  23. Narayan O., Clements J. E., Griffin D. E., Wolinsky J. S. 1981; Neutralizing antibody spectrum determines the antigenic profiles of emerging mutants of visna virus. Infection and Immunity 52:1045–1050
    [Google Scholar]
  24. Narayan O., Sheffer D., Griffin D. E., Clements J., Hess J. 1984; Lack of neutralizing antibodies to caprine arthritis-encephalitis lentivirus in persistently infected goats can be overcome by immunization with inactivated Mycobacterium tuberculosis. Journal of Virology 49:349–355
    [Google Scholar]
  25. Oliver R. E., Gorham J. R., Parish S. F., Hadlow W. J., Narayan O. 1981a; Ovine progressive pneumonia: pathologic and virologic studies on the naturally occurring disease. American Journal of Veterinary Research 42:1554–1559
    [Google Scholar]
  26. Oliver R. E., Gorham J. R., Perryman L. E., Spencer G. R. 1981b; Ovine progressive pneumonia: experimental intrathoracic, intracerebral and intraarticular injections. American Journal of Veterinary Research 42:1560–1564
    [Google Scholar]
  27. Oliver R. E., Adams D. S., Gorham J. R., Julian A. F., McNlven R., Muir J. 1982; Isolation of caprine arthritis-encephalitis virus from a goat. New Zealand Veterinary Journal 30:147–149
    [Google Scholar]
  28. Pálsson P. A. 1976; Maedi and visna in sheep. In Slow Virus Diseases of Animals and Man pp 17–43 Edited by Kimberlin R. H. Amsterdam: North-Holland;
    [Google Scholar]
  29. Perk K. 1982; Slow virus infections of ovine lung. Advances in Veterinary Science and Comparative Medicine 26:267–287
    [Google Scholar]
  30. Pétursson G., Nathanson N., Georgsson G., Panitch H., Pálsson P. A. 1976; Pathogenesis of visna. I. Sequential virologic, serologic and pathologic studies. Laboratory Investigation 35:402–412
    [Google Scholar]
  31. Pyper J. M., Clements J. E., Molineaux S. M., Narayan O. 1984; Genetic variation among lentiviruses: homology between visna virus and caprine arthritis-encephalitis virus is confined to the 5′ gag-pol region and a small portion of theenv gene. Journal of Virology 51:713–721
    [Google Scholar]
  32. Querat G., Barban V., Sauze N., Filippi P., Vigne R., Russo P., Vitu C. 1984; Highly lytic and persistent lentiviruses naturally present in sheep with progressive pneumonia are genetically distinct. Journal of Virology 52:672–679
    [Google Scholar]
  33. Roberson S. M., Cheevers W. P. 1984; A physical map of caprine arthritis-encephalitis provirus. Virology 134:489–492
    [Google Scholar]
  34. Roberson S. M., McGuire T. C., Klevjer-Anderson P., Gorham J. R., Cheevers W. P. 1982; Caprine arthritis-encephalitis virus is distinct from visna and progressive pneumonia viruses as measured by genome sequence homology. Journal of Virology 44:755–758
    [Google Scholar]
  35. Scott J. V., Stowring L., Haase A. T., Narayan O., Vigne R. 1979; Antigenic variation of visna virus. Cell 18:321–327
    [Google Scholar]
  36. Shapiro S. Z., August J. T. 1976; The use of immunoprecipitation to study the synthesis and cleavage processing of viral proteins. Journal of Immunological Methods 13:153–159
    [Google Scholar]
  37. Stowring L., Haase A. T., Charman H. P. 1979; Serologic definition of the lentivirus group of retroviruses. Journal of Virology 29:523–528
    [Google Scholar]
  38. Sundquist B. 1981; Goat visna virus: isolation of a retrovirus related to visna virus of sheep. Archives of Virology 68:115–127
    [Google Scholar]
  39. Vigne R., Filippi P., Querat G., Sauze N., Vitu C., Russo P., Delori P. 1982; Precursor polypeptides to structural proteins of visna virus. Journal of Virology 42:1046–1056
    [Google Scholar]
  40. Weiss M. J., Sweet R. W., Gulati S. C., Harter D. H. 1976; Nucleic acid sequence relationships among ‘slow’ viruses of sheep. Virology 71:395–401
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-66-6-1233
Loading
/content/journal/jgv/10.1099/0022-1317-66-6-1233
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error