@article{mbs:/content/journal/jgv/10.1099/0022-1317-66-6-1233, author = "Gogolewski, Ruby P. and Adams, D. Scott and McGuire, Travis C. and Banks, Keith L. and Cheevers, William P.", title = "Antigenic Cross-reactivity between Caprine Arthritis-Encephalitis, Visna and Progressive Pneumonia Viruses Involves All Virion-associated Proteins and Glycoproteins", journal= "Journal of General Virology", year = "1985", volume = "66", number = "6", pages = "1233-1240", doi = "https://doi.org/10.1099/0022-1317-66-6-1233", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-66-6-1233", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "lentiviruses", keywords = "cross-reactivity", keywords = "immunoprecipitation", abstract = "SUMMARY Antigenic relatedness between the virion-associated proteins of caprine arthritis-encephalitis, visna and progressive pneumonia viruses was examined. Antigenic cross-reactivity was assessed by immunoprecipitation of disrupted, radiolabelled virus with goat, sheep and rabbit antisera, followed by resolution of the immunoprecipitation products by SDS-polyacrylamide gel electrophoresis. The results indicate that antigenic cross-reactivity between the caprine and ovine virus isolates involves all of the major virion-associated proteins and glycoproteins. The common antigenic determinants exhibited by virion structural proteins are immunogenic in goats, sheep and rabbits.", }