1887

Abstract

SUMMARY

F-IF cells, which are more resistant to the anticellular and antiviral action of human α and β interferons (IFN-α and IFN-) than the parental RSa cells, were also found to be more resistant to both the anticellular and antiviral effect of IFN-. A high level of 2–5A synthetase was induced by treatment with IFN-α or -, but induction of 2–5A synthetase was not detected after IFN- treatment of the cells. F-IF cells had less than half the number of specific binding sites for IFN-α than the parental RSa cells.

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1984-06-01
2022-01-22
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