@article{mbs:/content/journal/jgv/10.1099/0022-1317-65-6-1113, author = "Morinaga, Naoko and Yonehara, S. and Kuwata, T.", title = "Cross-resistance to Human Interferon-γ of Human Interferon-β-resistant F-IFr Cells", journal= "Journal of General Virology", year = "1984", volume = "65", number = "6", pages = "1113-1117", doi = "https://doi.org/10.1099/0022-1317-65-6-1113", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-65-6-1113", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "cross-resistance", keywords = "β and γ", keywords = "interferon", keywords = "human α", abstract = "SUMMARY F-IFr cells, which are more resistant to the anticellular and antiviral action of human α and β interferons (IFN-α and IFN-β) than the parental RSa cells, were also found to be more resistant to both the anticellular and antiviral effect of IFN-γ. A high level of 2–5A synthetase was induced by treatment with IFN-α or -β, but induction of 2–5A synthetase was not detected after IFN-γ treatment of the cells. F-IFr cells had less than half the number of specific binding sites for IFN-α than the parental RSa cells.", }