1887

Abstract

Summary

Mice immunized with ultraviolet-inactivated herpes simplex virus (HSV) or injected with infectious virus developed IgE-specific antibody to HSV. Cell-bound IgE was detected by measuring the release of histamine from peritoneal mast cells challenged with virus antigens. Circulating IgE antibody was detected by sensitizing rat basophilic leukaemia (RBL-2H3) cells with sera from HSV-immunized mice and then challenging these cells with virus or control antigens to release histamine. IgE antibody may contribute to the pathogenesis of virus infections.

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/content/journal/jgv/10.1099/0022-1317-64-3-533
1983-03-01
2019-10-20
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-64-3-533
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