An Epstein-Barr virus (EBV)-like herpesvirus has been isolated from a baboon cell line (594S/F9) by induction with the tumour promoter 12--tetradecanoylphorbol-13-acetate (TPA). The herpesvirus papio (HVP) DNA was mixed with B95 EBV DNA and was characterized by sedimentation in neutral glycerol gradient as 55S DNA, with a buoyant density of approx. 1.718 g/ml after equilibrium centrifugation in caesium chloride. DNA-DNA reassociation kinetics between B95 EBV and HVP DNA showed that HVP DNA shares about 40% homology with B95 EBV DNA. Blot hybridization of RI fragments of HVP DNA with a P-B95 EBV DNA probe showed that most of the RI fragments of HVP DNA were hybridized to B95 EBV DNA, suggesting that the homologous sequences were dispersed throughout the virus DNA.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error