1887

Abstract

Summary

Spontaneous production of endogenous xenotropic viruses by clones of New Zealand Black (NZB) embryo cells occurs at a constant level even after several cell transfers. Foci of cell alteration occur spontaneously in some of the clonal lines after 6 to 10 passages. The amount of virus generated does not correlate with spontaneous transformation of these NZB cells nor of cells from NIH Swiss or BALB/c mice. The data demonstrate an intracellular regulation of xenotropic virus expression which remains stable over several cell generations and differs from that controlling cell transformation.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-39-3-427
1978-06-01
2019-11-13
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-39-3-427
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error